Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"Cis-Element"”.
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Identification of a Minimal Cis-element and Cognate Trans-factors Required for the Regulation of Rac2 Gene Expression during K562 Cell Differentiation
… differentiation and identification of a minimal cis-element required for the induction of Rac2 gene expression during K562 cell differentiation. The Rho family GTPase Rac2 is expressed in hematopoietic cell lineages and is further up-regulated upon terminal myeloid cell differentiation. Rac2 …
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SEQUENCE ELEMENTS ESSENTIAL FOR RNA EDITING IN CHLOROPLASTS
… this in vitro assay, the essential sequence elements for editing were delimited to a region containing sequences of rpoB that are shared with two other editing sites. Wild-type substrates were edited to a greater extent in vitro compared to substrates with nucleotide differences in the common …
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Exercise-induced protection against insulin resistance and type 11 diabetes : the role of calcium
Regular exercise protects individuals against developing insulin resistance and type II diabetes. This effect of exercise does not appear to be due to an improvement in the insulin signalling pathway but instead due to an increase in the content of the insulin-regulatable glucose transporter …
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Regulation of outer surface lipoprotein A in the Lyme disease spirochete Borrelia burgdorferi
… of the ospA promoter was determined to be a cis-element essential for both the full expression and full repression of ospA.
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Tissue-specific classification of alternatively spliced human exons
… nonsense-mediated mRNA decay caused by skipping. Cis-element motifs that might bind protein factors that affect splicing were identified using overrepresentation analysis and conserved occurrence rate between human and mouse.
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Towards Identifying Cis and Trans Regulators of Expression of Xylem Cysteine Protease 1 (XCP1) in Arabidopsis
… water-conducting cells known as tracheary elements. Understanding tracheary element differentiation and maturation is of scientific and commercial importance as it may lead to broad understanding of cellular differentiation processes as well as ways to increase both the quality and quantity …
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Regulation of IGFBP-5 and Osteoblast Functions by Nuclear Factor I
… activity was mediated by a composite response element that has binding sites for transcription factor activator protein 2 (AP-2) and nuclear factor I (NFI). The work in this dissertation identifies the NFI gene family as an important regulator of IGFBP-5 transcription primarily in human, as …
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Studies on the Regulation of Acetyl-CoA Carboxylase and its Influence on Bacillus subtilis Differentiation
… of sporulation, Spo0A. Binding of Spo0A to a cis-element (0A box) in the promoter region of the operon has recently been identified as a strict requirement for biofilm formation and sporulation, two widely-studied cell differentiation processes which occur after the exponential growth phase. …
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Promoter Deletion Analysis of Xylem Cysteine Protease 2 (XCP2) in Arabidopsis thaliana
The process of xylem tracheary element differentiation involves the coordination of vascular cambium activity, cell fate determination, cell expansion/elongation, secondary wall synthesis, programmed cell death, and cellular autolysis. The end result of tracheary element differentiation is a …
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Dissecting Transcriptional Regulation of Rpp8 in Arabidopsis thaliana
… invading pathogens. R proteins must be precisely regulated to provide effective resistance, without inhibiting normal plant growth. However, little is known about R gene regulation under defense-inducing conditions. The interaction between the oomycete Hyaloperonospora parasitica and the …
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Establishment of the epigenetic landscape in mammalian embryonic stem cells
… genomics approach to elucidate the role of cis elements in the establishment of repressive chromatin domains. To this effect, we determined the genetic basis for localization of Polycomb repressive complexes (PRCs) in mammalian embryonic stem (ES) cells. First, by generating genomewide …
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Circadian regulation and phytohormone responses of cytochrome P450 monooxygenase genes in Arabidopsis
… methyl jasmonate (MeJ), salicylic acid (SA), abscisic acid (ABA) and indole-3-acetic acid (IAA). My analysis of transcript profiles of seedlings treated with individual hormones indicated the responses of many P450 genes to these hormone treatments are gated by circadian clock. And different …
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Structure and Function Analysis of a Plant Transcription Activator
… mosaic virus 35S promoter is composed of several cis-elements, each of which confers a different expression pattern in transgenic tobacco. One such cis-element, activation sequence (as)-1 (-83 to -63) mediates preferential expression in root. The element contains a tandem repeat of the motif …
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Analyse der in-vivo Funktion der Transkriptionsfaktoren TGA2.1 und TGA2.2 aus Tabak nach Fusion mit einer konstitutiven Aktivierungsdomäne
… SA-induzierbaren Promotoren findet sich das cis-Element activating sequence 1 (as-1). An dem Proteinkomplex ASF-1 / SARP, der an as-1 und as-1-ähnliche Elemente bindet, sind die bZIP-Transkriptionsfaktoren TGA2.1 und TGA2.2 beteiligt. Eine SA-abhängige Veränderung der Bindungseigenschaften …
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Isolation and characterization of latex-specific promoters from Papaver somniferum L.
… LSPs were sequenced and analyzed for regulatory elements using the Plant cis-acting regulatory DNA elements database, PLACE (http://www.dna.affrc.go.jp/PLACE). Knowledge of the cis-elements and regulatory regions of LSPs would serve as a tool for metabolic engineering of poppy alkaloids. …
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Caracterização molecular da resistência à ferrugem asiática da soja mediada pelo gene Rpp4
… Além disso, utilizando a ferramenta Clover (cis-element over representation) e TRANSFAC (transcription factor database) identificamos 33 sitios para fatores de transcrição presentes nos promotores dos genes diferencialmente expressos. Finalmente, para elucidar quais os genes são …
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Functional characterization and analysis of Carica papaya SHORT VEGETATIVE PHASE (CpSVP)
… in pedicels. We identified a GA response cis-element, a pyrimidine box (P-box) at -461 bp, that enhances CpSVP expression and pedicels with no effect on flowering time, elongating pedicels only for CpSVP-Y allele. Determining the gene responsible for peduncle elongation will enhance our …
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Elucidation of Jasmonate-Responsive Promoter Elements in the Calmodulin-Like Gene CML39 in Arabidopsis
… predict a large number of putative JA-responsive cis-elements within the CML39 promoter. Deletion analysis of CML39 promoter fragments in planta reveals that some cis-elements respond in a tissue-specific manner. Analysis of transgenic MYC2 loss-of-function (myc2) mutants demonstrates that MYC2 – …
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The Role of ORF59 and PAN ENE in Viral Replication of KSHV
… expression and immune response. PAN possess two cis-acting elements, the MRE (Mta-response element) and the ENE (expression and nuclear retention element). While PAN has been shown to be required for viral replication, the function of these elements within PAN remains elusive. In our studies, we …
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Identification and functional characterization of microRNA regulatory elements in Brassicaceae
… evolutionary tem, and identify the most relevant cisregulatory elements in some microRNAs for improving the agriculture in the future, this study was carried out. microRNA390 is one of the many conserved microRNAs, it can indirectly regulate the ARFs expression level by targeting TAS3, and …
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