Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Circulating biomarker"”.
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Defining the human immune signature following infection with Crimean-Congo haemorrhagic fever virus
… two years and were analysed for antibody, serum circulating biomarker and T-cell memory responses. The studies demonstrated that neither IgM nor IgG antibodies were raised to CCHFV antigens in patients with severe disease despite each patient surviving for long enough such that a suitable immune …
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Novel imaging and blood biomarkers in acute aortic syndrome
… tomography and computed tomography (PET/CT) and circulating biomarkers in patients with acute aortic syndrome. METHODS: We performed 18F-sodium fluoride PET/CT in 56 patients with aortic dissection, intramural haematoma or penetrating aortic ulcers and 20 healthy controls. First, we characterised …
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Evaluating Magnetic Resonance Imaging and Serum Markers As Surrogate Endpoints for Clinical Trials in Cerebral Small Vessel Disease
… Recently there has also been growing interest in circulating biomarkers such as serum neurofilament light chain as they are easier to obtain from patients than imaging markers and as they can be centrally computed also in multicenter trials. The thesis aim is to evaluate imaging as well as …
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Ultrasensitive quantification of circulating disease biomarkers through enzymatic labeling and single molecule counting
… methods for quantifying low abundance biomarkers with the ultimate goal of developing robust tools for advancing disease diagnosis. In recent years there has been an immense expansion in the identification of sensitive and specific indicators of disease. As our understanding of these …