Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Circadian Rhythm Disruption"”.
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Investigation into the molecular mechanisms underlying circadian rhythm disruption and human cancer
… of the core mammalian clock factors known to be rhythmically expressed throughout the body and directly binds to the tumor suppressor p53 and its negative regulator, the oncogenic mouse double minute-2 (MDM2) protein. PER2 modulates p53 transcriptional activity by preventing MDM2-mediated …
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Glymphatic flow diurnal variation in the brain inhibited by circadian rhythm disruption and recovered by arginine vasopressin administration
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-05-01
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Breast Cancer and Cortisol Secretion in Relation to the Per3 Vntr, Chronotype, and Sleep
<p>Background: Circadian rhythm disruption, sleep abnormalities, and shift work have emerged as cancer risk factors. Genetic variation of clock genes, which aid in circadian rhythm control, may increase cancer susceptibility or lead to disruption of hormone secretion. A Period 3 (Per3) clock gene …
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Aptamer-Based Detection of Salivary Melatonin for Circadian Rhythm Sleep Disorders Monitoring
Circadian rhythms sleep disorders are linked to the disruption of daily levels of circulating melatonin. Current circadian rhythm sleep disorder diagnostic approaches are typically based on questionnaires (which lack objectivity), and/or on dim light melatonin onset tests (which are costly, …