Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 49 for “"Chronic wounds"”.
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Itch occurring with chronic wounds
<p>Abstract</p>
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Antimicrobial wafers as a novel technology for infection control in chronic wounds.
… impaired wound healing. Generally, non-healing wounds display similar physiological features with regards to mixed bacterial flora, ischemia and production of exudate. The application of topical, broad spectrum antimicrobial compounds embedded in absorbent dressings has been shown to control …
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Design of a multi-functional, nanoparticles-loaded supramolecular hydrogel to treat chronic wounds
L'abstract è presente nell'allegato / the abstract is in the attachment
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Assessment of in vitro engineered microvascular networks and their application in the treatment of chronic wounds
… in the nearer term application of treating chronic wounds will also be assessed, and a potential business strategy will be laid out.
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Identifying barriers to accessing healthcare for chronic wounds in the Khayelitsha sub-district: a mixed methods study
Background: Chronic wounds impose a significant burden on health systems, as delayed access to care contributes to poorer clinical outcomes and increased healthcare costs. These delays are particularly pronounced within resource-constrained systems such as the South African public healthcare …
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Surface Engineered Novel Patterned Polymers to Remove Pathogenic Biofilms from Human Skin. Effective Removal of Antimicrobial Resistant Bacteria from Chronic Wounds
A silent pandemic, chronic, non-healing wounds are a major cause of morbidity, with treatment and management representing significant health burdens. The opportunistic pathogens Staphylococcus aureus and Pseudomonas aeruginosa are the most common species isolated from chronic wounds. …
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Using Optimal Control Theory to Optimize the Use of Oxygen Therapy in Chronic Wound Healing
… million people in the United States suffer from chronic wounds, which are defined as wounds that do not heal in 30 days time; an estimated $25 billion per year is spent on their treatment in the United States. In our work, we focused on treating chronic wounds with bacterial infections using …
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PREPARATION AND CHARACTERIZATION OF AN ELECTROSPUN GELATIN/DENDRIMER HYBRID NANOFIBER DRESSING
… and characterized for its potential to treat chronic wounds. Comprised of gelatin, dendrimer, synthetic polymer and antibiotics, the dressing was electrospun to mimic the natural extracellular matrix (ECM). Gelatin is biocompatible, biodegradable, non-toxic, and easily available. The …
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Induction of Heme Oxygenase By a Carbon Monoxide-Releasing Molecule
… that heme oxygenase is expressed in both healing wounds and in pressure ulcers. Heme oxygenase has been shown to have important cytoprotective functions in myocardial ischemia-reperfusion injury and organ allograft survival. The cytoprotective effects of heme oxygenase are multifactorial. Besides …
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Borate based bioactive glass scaffolds for hard and soft tissue engineering
… material that may be useful in the treatment of chronic wounds. A full thickness cutaneous defect (15mm diameter) on the back of a laboratory rats were healed in similar time (18 days), but with a higher quality scar than the control (untreated wound). The results from the full thickness …
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The effect of Stromal cell Derived Factor-1 (SDF-1) and collagen-GAG (Glycosaminoglycan) scaffold on skin wound healing
… Wound care is a significant clinical problem for chronic wounds (eg. diabetic ulcers), acute injuries (eg. burns) and in elective surgeries (eg. scar revision). With an overall annual cost of $16 - 22 billion, wounds severely burden the U.S. healthcare system, and are the fastest growing area in …
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Success and limitations of gene therapy with growth factors to enhance cutaneous wound healing
Chronic wounds are a major source of morbidity - causing pain, suffering, and disability. One of the reasons for their abnormal healing appears to be a reduction in the availability of growth factors within chronic wounds. The application of growth factors to wounds has had only limited success in …
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How adults with type 2 diabetes and a chronic lower extremity wound understand the link between their wound and their diabetes management
… do people with type 2 diabetes who also have a chronic lower wound understand about the management of their condition and the complication of a wound? With the number of people with type 2 diabetes in New Zealand growing so rapidly so are the number of people experiencing complications …
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Laser-processed parchment paper for fabrication of chronic wound dressings with selective oxygenation
<p>Chronic non-healing wounds (e.g., diabetic foot ulcers and bed sores) impact over 6.5 million Americans per year, costs in excess of $25 billion to treat on an annual basis, and are on the rise due to increasing levels of obesity and diabetes compounded by an aging population. A major inhibitor …
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Design and development of a positioning robot for use as a surgical debridement method
… the act of removing dead tissue and debris from wounds, is critical to ensure the wound healing process is resumed in chronic wounds and wounds that are stuck in the healing process. This thesis investigates the positional accuracy of a positioning robot for future development as a hydro-surgical …
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Early Mediators of Cutaneous Ischemia Reperfusion Injury: A Mouse Model
Chronic tissue injuries present an enormous problem to both patients and healthcare professionals, and yet little is definitively known as to the underlying pathophysiology. While there are numerous comorbidities associated with these wounds, a unifying theme has been proposed to be the repetitive …
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A tissue tensioner to limit water injection during high pressure water jet debridement
… necrotic tissue and foreign materials from wounds is a critical step in the management and treatment of chronic wounds. MIT's BioInstrumentation Laboratory developed a novel debridement technology that uses two high-speed impinging water jets to excise necrotic tissue. However, this device …
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A device for debridement using high pressure water jets
Removing devitalized tissue from chronic wounds through debridement is critical to promote wound healing. In this thesis, technology using high-speed water jets is explored toward applications for debridement. After presenting possible techniques, the thesis expands on one promising method using …
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Šiuolaikinis lėtinių apatinių galūnių opų gydymas /
Chronic lower extremity ulcers are associated with a significant financial, psychological, and social burden for both the individual and society. With an aging population and the earlier emergence of Western lifestyle-related diseases, the prevalence of patients afflicted with chronic lower limb …
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