Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"Chronic traumatic encephalopathy"”.
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The role of Substance P in chronic traumatic encephalopathy
Chronic traumatic encephalopathy (CTE) is believed to be a neurodegenerative disease associated with contact sports and exposure to repetitive mild traumatic brain injury (rmTBI). CTE has attracted significant attraction over the past few years due to the high incidence of sports-related head …
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Understanding the experiences of caregivers for patients with Chronic Traumatic Encephalopathy
… the experiences of caregivers for patients with Chronic Traumatic Encephalopathy (CTE) and develop an informative resource to help support these caregivers. Literature on caregiving in other contexts (i.e. neurodegenerative diseases) has consistently shown the prevalence of caregiving burden, and …
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Predictors of Chronic Traumatic Encephalopathy in NFL Players: A Meta Analysis Review
<p>Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease that emerges as a result of repetitive mild traumatic brain injury and has been studied within athletes of all sports. Repetitive blows to the brain are associated with many pathological changes and an emergence of …
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Investigating the Use of [18-F] tau-PET Imaging as a Biomarker of tau Pathology in Retired Athletes at Risk of Neurodegeneration
… as seen in Alzheimer’s disease and chronic traumatic encephalopathy. Chronic traumatic encephalopathy is characterized by abnormal accumulation of tau protein in the brains of affected athletes in a pattern distinct from other neurodegenerative diseases. There is currently no in vivo …
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Invisible scars : how domestic violence victims have been left out of the discussion on traumatic brain injuries
Traumatic brain injuries are one of the most common injuries in domestic violence, with studies finding that approximately 75 percent of women tested report at least one TBI. These injuries leave invisible scars in the form of memory problems. But despite the large prevalence of TBIs in the …
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Converging Pathways: Neuroimmunology of Tauopathy and Mild Traumatic Brain Injury
… correlates with the neurodegenerative disease Chronic Traumatic Encephalopathy. Because rising evidence has linked innate and adaptive immunity to neurodegenerative diseases, in this thesis, I set out to map the immune responses of a primary tauopathy and repeat head injury. Using high …
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Subconcussive blows in high school football : putting young brains at risk
… even as public awareness of concussions and chronic traumatic encephalopathy (CTE) reaches new heights, subconcussive blows continue to fly under the radar. For the past seven years, the PNG has run their research on a shoestring budget, and now, at the end of their funding, they are running …
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Cognitive Performance In A Retired NFL Population: Does Position Played And Racial Identity Impact Cognition?
… and psychosocial outcomes following a traumatic brain injury, there are few studies that have explored the factors that affect long-term effects of playing football through using a comprehensive neuropsychological battery. As emerging studies continue to shed light on the association …
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Modeling subconcussive and cumulative subconcussive impacts using a lateral fluid percusion injury device
… consequences, such as dementia. Recently, chronic traumatic encephalopathy (CTE) has gained momentum in the science and medical community as a neurodegenerative disease of repetitive head injuries. CTE was observed at autopsy of former athletes that did not closely correlate with a clinical …
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The Effect of Traumatic Brain Injury On Tau Pathology By A Potential Seeding Mechanism
… such as Alzheimer’s disease (AD) and chronic traumatic encephalopathy (CTE), among others. Misfolded tau engenders a structurally alternative intermediate conformation that is prone to aggregate having amyloidogenic properties. Formation of amyloids, such as tau aggregates, is proposed …
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Traumatic Brain Injury As An Environmental Risk Factor For Neurodegeneration: Elucidating Causal Mechanisms With Drosophila
Traumatic brain injury (TBI) is one of the leading causes of mortality and disability worldwide. TBI is not just the primary insult caused by a mechanical force impacting the head, but is a complex disease process with repercussions that continue to develop decades after the injury. There are no …
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Methods and algorithms for quantitative analysis of metallomic images to assess traumatic brain injury
… to quantitatively determine the link between traumatic brain injury (TBI) severity and chronic traumatic encephalopathy (CTE) neuropathology, specifically looking into the role of blood-brain barrier disruption following TBI. In order to causally investigate the relationship between the tau …
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Amyloid seeding assays for the selective amplification of tau aggregates from human brain homogenates
… of 3R/4R tau aggregates (Alzheimer disease, AD; chronic traumatic encephalopathy, CTE; primary age-related tauopathy, PART). This work details several methods for the selective detection and amplification of tau aggregates from human brain homogenates. This approach uses the self-propagating …
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Structural studies of the in vitro assembly of tau and α-synuclein amyloids
… folds observed in Alzheimer’s Disease (AD) and Chronic Traumatic Encephalopathy (CTE). These findings are the first to describe the formation of disease specific structures of any amyloid, using recombinant protein *in vitro*. The conditions identified in this study can be used for the …
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Transcranial Administration of Nano Pulse Laser Therapy for Blast Induced Neurotrauma
Treatment and care for mild traumatic brain injury (mTBI) is often overlooked in TBI research, yet it is the most common form of TBI. Moderate-severe TBI is accompanied by distinct behavioral and physiological characterizations, while mTBI presents variably. mTBI is a promising target for …
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Cognitive, Psychiatric, And Neuropathological Manifestations Of Repetitive Mild Traumatic Brain Injury
… on the brain become magnified. Repetitive mild traumatic brain injury (rmTBI) has been linked to the development of chronic traumatic encephalopathy (CTE). The neurodegeneration accompanying CTE occurs over many years following repeated head impacts and is characterized by progressive brain …
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The effect of repetitive head impact exposure on white matter lesion volume
Contact and collision sports (CCS) expose athletes to countless repetitive head impacts (RHI) across a single season, potentially leading to increased risk of long-term difficulties in cognition and the development of neurodegenerative disease. There is mixed literature on whether RHI from CCS …