Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Chronic intermittent ethanol."”.
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Chronic intermittent ethanol treatment yields persistent increases in anxiety and receptor subunit changes in adolescent and adult rats.
… are involved in the behavioral effects of ethanol; however, the age-dependent molecular mechanisms associated with the effects of chronic ethanol have yet to be fully elucidated. Adolescence is marked by unique sensitivity to certain effects of ethanol, including distinct consumption …
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EXAMINING SEX DIFFERENCES IN NEUROBIOLOGICAL AND BEHAVIORAL CHANGES INDUCED BY CHRONIC INTERMITTENT ETHANOL VAPOR EXPOSURE IN LONG EVANS RATS
Chronic intermittent ethanol (CIE) treatment is known to produce changes in synaptic plasticity and excitability in animal models. Data from our lab suggests that withdrawal from CIE exposure induces an increase in anxiety-like behavior and an increase in hippocampal excitability in male rats. We …
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The effects of chronic intermittent ethanol exposure on fear conditioning in rats: an investigation of the comorbidity of PTSD and AUD
… to the mouse study, we tested the effect of chronic intermittent ethanol (CIE), a model of alcohol dependence, on fear conditioning, a model of fear learning that engages circuits that are dysregulated in PTSD, in male Long Evans rats. We further expanded this research by looking at the …
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The effects of chronic intermittent ethanol exposure on withdrawal related behaviors, dopamine terminal function and kappa opioid system sensitivity in the nucleus accumbens core
… and health concern in the United States. Chronic alcohol use and abstinence is often followed by relapse to ethanol drinking occurs in response to the withdrawal symptoms of the drug. However, the neurobiological underpinnings of this disorder are not well understood. Previous work has …
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Ethanol priming and its effects on consumption and accumbal plasticity
… concerns in the United States because of their chronic, detrimental health effects and societal costs. The mesocorticolimbic pathway and the nucleus accumbens (NAc), in particular, play critical roles in the formation of drug dependence and expression of drug related behaviors. The NAc contains …
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Ethosuximide stabilizes sleep-related oscillations and reduces sleep fragmentation during alcohol withdrawal
… my dissertation is the study of the effects of ethanol on brain rhythms, measured by electroencephalography (EEG), as they pertain to alcohol withdrawal-related insomnia (AWI). AWI is an important clinical problem for chronic alcoholics undergoing treatment for alcoholism. The severity of AWI is …
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A STUDY ON THE EFFECTS OF CHRONIC ALCOHOL AND WITHDRAWAL IN THE BASOLATERAL AMYGDALA OF SPRAGUE DAWLEY RATS: AFFERENT SPECIFIC MODIFICATION OF GLUTAMATERGIC NEUROTRANSMISSION
… glutamatergic afferents into the BLA following chronic intermittent ethanol exposure (CIE) and withdrawal (WD). The current studies indicated that EC-BLA and IC-BLA inputs into the BLA can be electrically isolated in an electrophysiological slice recording setup, and remain isolated in the face …
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A Study on the Effects of Chronic Alcohol and Withdrawal on the Glutamate, GABA, and Dopamine Systems in the Basolateral Amygdala of Sprague Dawley Rats
… these two systems are significantly altered by chronic alcohol and withdrawal, resulting in ‘hyperexcitable’ BLA-output and anxiety-like behavior. Furthermore, the BLA inhibitory GABA system is modulated by the midbrain via the dopamine system, suggesting another potential target for the effects …