Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 50 for “"Chronic Heart Failure"”.
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Women's Experiences With Chronic Heart Failure
… approximately 4.1 million Americans suffer from chronic heart failure accounting for estimated direct and indirect costs of over $21 billion spent annually for health care. The incidence of heart failure has doubled each decade since the 1940's and slightly more men were inflicted with the …
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Long Term Therapy of Chronic Heart Failure
Chronic Heart Failure (CHF), also known as Congestive Heart Failure, remains a major global health burden, requiring a thorough understanding of its complex pathophysiology and treatment. This thesis provides an in-depth review of the long-term management of CHF, beginning with its etiology and …
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Resistance training for patients with chronic heart failure
Chronic heart failure (CHF) patients are limited in functional capacity by muscle fatigue and breathlessness. The effects of resistance training on muscle strength and endurance and functional aerobic capacity were evaluated in 9 men (63 ± 11 years; mean ± s.d) with CHF (LVEF 26 ± 6%). Training …
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Insulin resistance, chronic heart failure and potential treatment
… resistant (IR) are highly prevalent among heart failure (HF) patients. There is now increasing evidence to suggest a bidirectional relationship between IR and HF. DM and IR not only lead to heart failure, but heart failure can also lead to the development of DM or IR.<br/><br/>The degree of …
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Investigations Related to Dietary Sodium in Chronic Heart Failure
… the primary dietary therapy for individuals with heart failure (HF); however, there is little information available to support or refute the use of sodium restriction to manage HF. The overall goal of this work was to generate data related to dietary sodium in patients with chronic HF that would …
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Skeletal muscle structure and metabolism in chronic heart failure
Chronic heart failure (CHF) patients have poor exercise tolerance, which does not correlate with impaired central function. Consequently factors other than impaired cardiac function must contribute to the exercise intolerance. Maladaptations in skeletal muscle appear to be a likely reason for the …
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Mechanisms and Management of Breathlessness in Chronic Heart Failure
… options limited. This is particularly true for heart failure in which dyspnoea is a cardinal symptom, even when the heart failure is optimally managed. This thesis aims to untangle mechanisms and utilise this knowledge to optimise heart failure management. It focuses on the potential of …
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The Illness Intrusiveness Model in Male Veterans with Chronic Heart Failure
Background: Individuals suffering from chronic heart failure (CHF) experience adaptive and psychosocial challenges that originate from disease symptoms, and these symptoms often disrupt individuals’ valued lifestyles and activities; this interference is called illness intrusiveness. The illness …
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Chewing gum : a potential strategy to relieve thirst in chronic heart failure
Thirst is a common and burdensome symptom of chronic heart failure which adversely affects health related quality of life and compliance to self-care practices such as fluid restriction. Despite this, research on thirst remains scarce and there is no standard approach to identify patients with …
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Cellular therapy for chronic heart failure: a key role for epicardial fibronectin
… cardiomyocyte loss, frequently leading to heart failure, with a 50% 5-year mortality. At subacute time points following MI, animal studies have shown ‘remuscularization’ of the damaged heart with human embryonic stem cell (hESC)-derived cardiomyocytes. Recently, outcomes were improved by …
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AN EXPANSION ON DIAGNOSTIC AND PROGNOSTIC MARKERS IN DOGS WITH ACUTE AND CHRONIC HEART FAILURE
… has increasingly highlighted the importance of heart failure (HF) as a complex clinical syndrome. By its definition, HF is a condition in which the heart is unable to maintain sufficient organ perfusion to meet the body’s needs. Consequent hemodynamic derangements turn into increased sympathetic …
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Effects of pentoxifylline on exercising skeletal muscle vascular control in rats with chronic heart failure
… in TNF-[alpha] and exercise intolerance in chronic heart failure (CHF). The pharmaceutical TNF-[alpha] synthesis suppressor pentoxifylline (PTX) reduces plasma [TNF-[alpha]] and improves left ventricular (LV) function in CHF rats, but the effects of PTX on skeletal muscle blood flow (BF) and …
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Exercise tolerance and skeletal muscle structure and function in patients with severe chronic heart failure
… are common symptoms experienced by patients with chronic heart failure (CHF). Historically it has been argued that central cardiopulmonary factors including pulmonary congestion and reduced lung compliance cause dyspnoea that limits the exercise tolerance of such patients. But recent studies have …
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Effects of acute and chronic exercise on forearm blood flow in patients with chronic heart failure
Chronic heart failure (CHF) is a life-threatening syndrome caused by inadequate cardiac function, which may lead to reduced peripheral blood flow, deconditioning and skeletal muscle atrophy. Initially, a study of the biological and technical reliability of the techniques used in the latter chapters …
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Responding to resynchronization : improving the impact of biventricular pacing in the management of chronic heart failure
… morbidity and mortality in a select group of heart failure patients. However, many questions remain unanswered concerning the selection of patients for CRT, how to assess response to CRT and the exact pathophysiological actions of CRT. This thesis investigates some of these questions. Chapter …
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Effects of nitrite infusion on skeletal muscle vascular control during exercise in rats with chronic heart failure
Chronic heart failure (CHF) reduces nitric oxide (NO) bioavailability and impairs skeletal muscle vascular control during exercise. Reduction of nitrite (NO[subscript]2-) to NO may impact exercise-induced hyperemia particularly in muscles with pathologically-reduced O[subscript]2 delivery. We …
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An Investigation of the Benefits of Palliative Care for Patients with Chronic Heart Failure at a Novel Hospital-Based Palliative Care Service.
INTRODUCTION: Heart failure is a chronic cardiac condition that would benefit from palliative care and yet palliative care is still mainly provided for people with cancer or HIV. Patients with end-stage heart failure experience similar clinical symptoms as patients with advanced cancer with …
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The acute effects of two different training models on markers of inflammatory activation and skeletal muscle injury in patients with chronic heart failure
Background: Patients with heart failure (HF) are characterized by exercise intolerance, breathlessness, fatigue and excessive neurohormonal activation associated with premature mortality. Recently, inflammatory activation has been described as an important factor in the progression of HF. Increased …
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