Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1597 for “"Chromosome"”.
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Chromosome evolution in Lepidoptera
… all animals, plants and fungi is organised into chromosomes. While each species tends to have a fixed number of chromosomes in their genome, chromosome numbers vary widely across the tree of life. Changes in chromosome number occur due to rearrangements, such as the fusion and fission of …
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Chromosome partitioning in Bacillus subtilis
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Biology, 1999.
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Sex Chromosome Evolution in Blow Flies
… indicative of rapid evolutionary rates. Sex chromosome karyotypes are generally conserved within families; however, many species have derived sex chromosome configurations. Insects display a plethora of sex chromosome systems due to rapid diversification caused by changes in evolutionary …
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Molecular Mechanisms Involved in Chromosome Segregation
… macromolecular machines to accurately pass chromosomes to two daughter cells during cell division. Errors during chromosome segregation are frequently deleterious to the cell and often result in aneuploidy leading to the formation of cancer cells. Kinetochores are large macromolecular …
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3D chromosome structure and chromatin proteomics
… by, highly organized three-dimensional (3D) chromosome structures. The first part of the work presented here describes the generation of 3D chromosome regulatory landscape maps of human naive and primed embryonic stem cells. To create these 3D chromosome regulatory landscape maps, genome-wide …
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Patterns and processes driving chromosome organization
… analysis of interaction maps generated from Chromosome Conformation Capture (3C) technologies. We begin by analyzing data generated using a novel Micro-C protocol and assess its performance in comparison to established Hi-C. New computation tools are developed to extract, quantify and compare …
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Sequence of the mouse Y chromosome
The mouse Y chromosome has been studied for over 50 years, from the early sex determination and immunological phenotypes attributed to it in the 1950s, to the several mouse Y permatogenic phenotypes and the sex ratio distortion phenotype that are still being studied today. However, even though the …
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Chromosome banding of German cockroach spermatocytes
A chromosome banding protocol for <u>Blattella germanica</u> speramtocytes was developed to reveal locations of constitutive heterochromatin (C-bands). Normality of the acid treatment used to denature basic (histone) proteins, temperature of the salt solution used to extract DNA from unhanded …
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Equine Spermatogenesis: Meiotic Chromosome Behavior and Recombination
… outcome of meiosis. It is essential for proper chromosome segregation and formation of normal haploid gametes. Analysis of recombination frequency and distribution are crucial for genomic and association studies. Any alteration of the recombination frequency and positioning can cause …
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Chromosome abnormalities and breaks in newborn twins
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Quantitative Analysis of Chromosome/Gene Spatial Distribution
… Untersuchung der räumlichen Anordnung von Chromosomen bzw. Genen im Verlauf der letzten Jahre möglich gemacht. Es wurden bereits Algorithmen zur Quantifizierung der räumlichen Anordnung von Chromosomen bzw. Genen entwickelt, wobei die meisten dieser Methoden jedoch auf zweidimensionalen …
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Conformation and dynamics of the mammalian chromosome
… towards this goal. We characterize the ensemble chromosome conformation in mouse embryonic stem cells, by measuring interaction, or contact, probabilities between distal genomic loci. We map and describe chromosome loops, consisting of two interacting CTCF sites co-bound by cohesin, that maintain …
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Chromatin structure of the inactive X chromosome
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Biology, 1999.
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Chromosome and Genome Evolution in Culicinae Mosquitoes
… exons from twenty-four scaffolds to the mitotic chromosomes from imaginal discs. This study resulted in the construction of a first physical map of the Ae. albopictus genome as well as mapping viral integration and polyphenol oxidase genes. Moreover, comparing our present Ae. albopictus physical …
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Identification and Characterization of Y Chromosome and M Locus Genes in Anopheles and Aedes Mosquitoes Using the Chromosome Quotient Method
… male-determining factor located on the Y chromosome in Anopheles mosquitoes or in a small Y-like region called the M locus in Aedes mosquitoes. Before my research, not a single gene from the Anopheles Y or Aedes M locus had ever been discovered. During the course of my undergraduate …
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X chromosome studies and breast and ovarian carcinoma
Skewed somatic X inactivation (XCI), X-linked gene overexpression and abnormal X content have been associated with breast and ovarian cancer. Partial or complete reactivation of the inactive X in females may be a step in breast and ovarian cancer progression, leading to overexpression of some …
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Probing Mitotic Chromosome Structure and Arrangement Using Micromanipulation
… muntjak), has the lowest known diploid chromosome number (seven in the male) for a mammal. Mitotic chromosomes can be removed from cells either by extraction with microneedles or by inducing chromosome expulsion with a drop of silicone oil applied to the cell. The entire diploid …
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