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Showing 1 to 9 of 9 for “"Chromones"”.
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Novel addition reactions of some benzopyrans
… cyanoborohydride and yields of 2-amino-3-alkylchromones in admixture with 3-hydroxy-3-(2-hydroxyphenyl)-2- alkylpropanonitriles. Lithium dialkynylcuprates were prepared and were successfully added, in a 1,4-fashion, to chromone-3-carbonitrile yielding …
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The development of new synthetic methods for chromone and ergochrome construction
… possess useful anti-tumour properties whilst chromones are useful drugs for the treatment of allergic asthma. The aim of the project was to synthesise ergoflavin or an analogue for the first time, and to this end novel synthetic methods for α,β-unsaturated ketones and oxygenated dienes were …
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Synthetic studies and biological evaluation of chromone - 3 - carbaldehydes
Chromones are well known naturally occurring heterocyclic compounds with oxygen as a heteroatom. Chromones are also one of the major classes of naturally occurring compounds, and the interest in their chemistry is due to their wide range of their biological activity. In this study, three classes of …
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Novel Photochemical Methodologies for Diversity Oriented Synthesis and Screening of Combinatorial Libraries
… <em>Diels-Alder</em> adducts based on various chromones. We discovered that the <em>Diels-Alder</em> adducts of chromones are capable of photoinduced alkene-arene [2+2] cycloaddition producing different dienes, which can either dimerize or be introduced into a double-tandem …
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Synthetic and spectroscopic studies of 6-substituted chromone derivatives
Chromones and chromone derivatives are naturally occurring compounds found in the plant kingdom; for example, baicalein was used as a diuretic and anti-allergic drug in ancient Chinese medicine. A range of chromone-2-carboxylic acids were synthesized from six substituted 2- hydroxyacetophenones. …
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Estudo ficoquímico e avaliação da atividade microbiológica de algas marinhas do gênero sargassum.
… can mention: alginates, florotaninos, coumarins, chromones, quinones, and terpenoids feoftinas . Studies have shown that metabolites produced by algae of the genus Sargass umtiveram biological activities, such as anticoagulant, antioxidant, analgesic and antipyretic . It is important to …
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Reactions and rearrangements of chroman-4-ones and related compounds
… to a range of hitherto inaccessible 3-alkenylchromones. The regio- and stereo-chemical outcome of the reaction has been elucidated. Some preliminary investigations of the behaviour of 3-alkenyl chromones in Diels-Alder reactions are described.
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Studies in Furobenzopyran Chemistry
A series of 3-acyl(thio)chromones has been prepared. These compounds were acetalised with a variety of diols, with p-TsOH catalysis, under azeotropic conditions, to give the corresponding 3-acyl(thio)chromone acetals. A new rearrangement accompanies the formation of acetals from 3-acetyl- or …
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Design and synthesis of potential chrome-based anti-tuberculosis agents
This dissertation describes the design and synthesis of 4-(4-oxochromen-3-yl)-3,4-dihydropyrimidin-2-one derivatives and the assessment of their biological activity against a strain of the causative agent of TB. In this investigation, two classes of chromone-based compounds were synthesised. …