Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Chromane"”.
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Computational studies of biomolecules to explore potential therapeutics for COVID-19 and SAMD9- associated diseases
… enhanced hydrophobic side chains attached to the chromane unit, and a CF₃ or OCF₃ functional group attached to the benzene ring contribute to increased binding affinities. Further, molecular dynamics simulation showed that complexes of compound FHT18-6c with non-structural protein 4 and …
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DESIGN, SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF NOVEL BIFUNCTIONAL COMPOUNDS
… (NONI and NDNI), whereas we chose 2-(aminomethyl)chromane (2-AMC) was the molecular portion endowed with the required D2/D3 receptor agonist properties. Bitopic compounds with the above cited molecular features should ideally inhibit dopamine release, a condition that could be exploited in …
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Isolation, Structure Elucidation, and Total Synthesis of Biologically Active Natural Products from Plants
As a part of the continuing search for bioactive compounds with the Madagascar International Cooperative Biodiversity Group (ICBG), and in collaboration with the Natural Products Discovery Institute of the Institute for Hepatitis and Virus Research (IHVR), thirteen plant extracts were investigated …