Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Chromaffin cells"”.
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Asymmetrical transmembrane potential in intracellular organelles of adrenal chromaffin cells exposed to nanosecond electric pulses
… electric pulses on neurosecretory adrenal chromaffin cells, cell modeling has played an important role in understanding and explaining the experimental results. Externally applied nanosecond-duration electric pulses (NEPs) can affect cells by creating nanopores in the cell and intracellular …
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5 ns Electric pulses evoke longer-lived calcium responses in adrenal chromaffin cells than the physiological stimulus: an experimental and computational study
… release from neuroendocrine adrenal chromaffin cells. The overall goal of this work is to understand why 5 ns, 5 MV/m pulses evoke longer-lived calcium responses than nicotinic cholinergic receptor activation, the physiological stimulus. In vivo, stimulation of chromaffin cells by …
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Co-Culture of Amphibian Adrenal Cells: A Model of Medullary Control of Corticosteroidogenesis
Chromaffin-adrenocortical cellular interactions have become recognized as an important component of adrenocortical regulation, however, the mechanisms by which chromaffin cells modulate adrenocortical function are not well understood. To study chromaffin-adrenocortical cellular interactions …
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The development and evolution of vertebrate oxygen-sensing cells
Oxygen-sensing cells release neurotransmitters, including serotonin, in response to hypoxia in the blood or surrounding air/water. This stimulates the glossopharyngeal and/or vagal nerves, triggering increased ventilation via the respiratory reflex. In the adult, they are located in the carotid …
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Munc18 function in large dense-core vesicle exocytosis
… large dense-core vesicle exocytosis in adrenal chromaffin cells. We combined complementary techniques (electrophysiology, electronmicroscopy) to assay docking, priming and Ca2+ triggered fusion of the vesicles. First, we further confirmed the view that Munc18-1 is a positive regulator of large …
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Dense Core Vesicle Heterogeneity in Anterior Pituitary Cells
… female lactotrophs, a distinct pattern emerges. Cells that retain prolactin cores after exocytosis correspond with those that contain synaptotagmin 1. This finding is a reversal for previous studies in chromaffin cells supporting the theory that not all dense core vesicles are the same across …
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Cell biology of settlement and adhesion processes of biofouling algae
… events were similar to those seen in bovine chromaffin cells with the presence of foot signals in the recordings implying a role for a ‘fusion pore’ in exocytosis. Using DAF-FM DA nitric oxide (NO) production in Seminavis robusta was found to be 4-fold greater on a surface to which the cells …
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Development of selective high-affinity fluorescent sensors for imaging neurotransmitters and application in cells and tissue
… and fluorescence) and their applications in cells and tissue. NeuroSensor 510 (NS510) was designed and synthesized as a selective sensor for imaging norepinephrine. Formation of both an iminium ion and a boronate ester gave high affinity upon binding NS510 to norepinephrine. The sensor was …
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An in vitro cell lineage model to identify alterations in the differentiation program of neuroblastoma
… solid tumor that arises from trunk neural crest cells (tNCCs), a transient cell population involved in the development of the sympathetic nervous system. The tNCCs are migrating cells that differentiate into sympathoadrenal precursors (SAPs) and Schwann cell precursors (SCPs). The SAPs are the …
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Plasticity of Adrenal Chromaffin Cell Function During Inflammation and Exposure to Microbe-Associated Molecular Patterns
… postganglionic sympathetic neurons and adrenal chromaffin cells (ACCs). Central autonomic structures receive information regarding the inflammatory status of the body and reflexively modulate SNS activity. Evidence suggests that inflammation and infection can also directly regulate ACC function. …
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Unraveling the Role of SNARE Interactions in Neurotransmitter Release
… a change in the Ca2+-dependence of secretion in chromaffin cells has no effect on the SNARE/synaptotagmin 1 interactions, but has a conspicuous effect on core complex assembly. Thus, the SNAREs are unlikely to directly act as Ca2+ sensors, but SNARE complex assembly is tightly coupled to Ca2+ …
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Electrochemical and microscopic analysis of chemical signalling in biological systems
… of how exocytosis is regulated in PC12 and chromaffin cells, along with how it is affected by pharmacological treatments as well as more intrinsic factors such as the secretory activity of the cell. In paper I, storage and release of dopamine was determined both using amperometry and imaging …
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Mechanisms of dendritic peptide release
… in other cell types such as bovine adrenal chromaffin cells were shown to segregate according to vesicle age, suggesting that vesicle age is an important factor in the regulation of peptide release. Whether vesicles of different age groups exist in magnocellular dendrites is not known. Thus, …