Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Chondrosarcoma"”.
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Inhibiting metastatic potential: an analysis of migratory body formation in chondrosarcoma
Chondrosarcoma (CHS) is the 2nd most prevalent bone sarcoma. Approximately 27% of all bone cancer cases reported to the International Agency for Research on Cancer (IARC) database are CHS. CHS tends to primarily affect adults above the age of 30 with 70% of cases reported affecting patients of 40 …
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Differential Gene Expression in Response to Hypoxia and Acidosis in Chest Wall Deformities and Chondrosarcoma
… for pectus excavatum, pectus carinatum, and chondrosarcoma are limited by our understanding of how these mechanisms operate. This study aimed to determine the roles of hypoxia and extracellular acidosis on the expression of genes related to the hypoxia response pathway in costal cartilage …
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Kazuistika fyzioterapeutické péče o pacienta po operaci subtrochanterického chondrosarkomu
… of a patient after surgery for subtrochanteric chondrosarcoma. Objectives: The objective of this thesis is a collection of theoretical and practical knowledge about chondrosarcoma and their application to a case study of patient, who is two years after the operation of chondrosarcoma on the …
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<i>PTHR1/SOX9</i> and <i>IDH1/IDH2</i> Relative Expression in Primary Chondrocyte and Chondrosarcoma Cells Under the Synergistic Influence of Inducible Hypoxia and Extracellular Acidosis
… gene expression in primary chondrocytes and chondrosarcomas. In this study, one primary chondrocyte cell line (CON5) and two chondrosarcoma grade II cell lines, JJ012-<em>IDH1</em> mutant and SW1353-<em> IDH2</em> mutant, were grown in four experimental conditions: hypoxia (5% O2), acidosis …
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Modular prosthetic reconstruction for primary bone tumours of the distal tibia in ten patients
… four with osteosarcoma and one with a low-grade chondrosarcoma. The patients with osteosarcoma had neo-adjuvant chemotherapy before surgery. Function was assessed by the Musculoskeletal Tumor Society (MSTS) score. Results: There were six females and four males, with a mean age of 31 (12-75) …
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Improving cancer therapy strategies via cellular stress and immune modulation
… (UPR). Preclinical studies in osteosarcoma (OS), chondrosarcoma (CS), and Ewing sarcoma (ES) demonstrated potent ErSO mediated cytotoxicity and anti-metastatic activity, significantly extending survival even in late stage, chemoresistant models. Mechanistic analyses revealed that ErSO activity is …
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Examining the Regulation and Function of Cancer Testis Antigens
… and seems to apply to other CTAs. Another CTA, Chondrosarcoma Associated Genes 1, was identified by a loss-of-function RNAi proliferation screen as a supporter of melanoma cell proliferation. CSAG1 is highly expressed in Melanoma lines with little to no expression in normal tissues. Additional …
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Identifizierung und funktionelle Analyse der humanen Xylosyltransferase I- und II-Promotoren
… of each promoter reporter gene construct in the chondrosarcoma cell line SW1353 and in the hepatoma cell line HepG2 revealed that a 797 bp fragment is essential for full XYLT1 promoter activity. In contrast, a region encompassing 177 nucleotides immediately upstream of the translation start site …
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The regulation of the T-box transcription factor TBX3 in Luminal A breast cancer
… at the E-boxes located at -1210 and -701 bps in chondrosarcoma and rhabdomyosarcoma cells. This study shows using qRT-PCR and western blotting, that when c-Myc is transiently depleted TBX3 mRNA and protein levels decrease. Importantly, when c-Myc is ectopically overexpressed in MCF-7 and T47D …