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Showing 1 to 2 of 2 for “"Cholinergic deficit"”.

  1. The Steroid Sulfatase Inhibitor (p-O-Sulfamoyl) - Tetradecanoyl Tyramine (DU-14) Enhances Memory Retention in Passive Avoidance in Rats with Hippocampal Cholinergic Deficit

    … retention for footshock in rats with hippocampal cholinergic hypofunction, male Sprague-Dawley rats were infused with the immunotoxin 192 IgG-saporin (SAP) into the medial septum, and tested using a step-through passive avoidance paradigm. There was a greater than 80% decrease in ChAT activity in …

    duquesne Repository record for The Steroid Sulfatase Inhibitor (p-O-Sulfamoyl) - Tetradecanoyl Tyramine (DU-14) Enhances Memory Retention in Passive Avoidance in Rats with Hippocampal Cholinergic Deficit (opens in a new tab)

  2. The Effect of Selective Cholinergic Lesion of Medial Septum on Recognition Memory

    … was to clarify the role of septal-hippocampal cholinergic neurons in object and spatial recognition memory. Stereotaxic-surgical infusion of the selective cholinergic neurotoxin, 192IgG-saporin (SAP), into the medial septum (MS) of Sprague-Dawley rats was utilized to establish an animal model …

    duquesne Repository record for The Effect of Selective Cholinergic Lesion of Medial Septum on Recognition Memory (opens in a new tab)