Global ETD Search
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Showing 1 to 16 of 16 for “"Cholesteatoma"”.
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Clinical Evaluation of Recurrent Cholesteatoma
OBJECT: Recurrent cholesteatoma is the term we have used to describe a cholesteatoma developing from a posterosuperior retraction pocket. Intact canal wall mastoidectomy provides relatively better hearing and no need of lifelong mastoid care while it causes higher recidivisim rate compared to open …
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Treatment of early middle ear cholesteatoma by atticosinoplasty
BACKGROUND AND OBJECTIVES: Treatment of early cholesteatoma usually involves surgical modification of mastoid antrum and tympanum to prevent recurrence. Reconstruction of ossicular chain and the ear drum after complete elimination of cholesteatoma in tympanum improves hearing greatly. However, like …
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Audit of outcomes of endoscopic cholesteatoma ear surgery
… becoming popular, there is scarce data on cholesteatoma recidivism and hearing outcomes, when exclusively used. Objectives: Auditing outcomes of endoscopic ear surgery for the surgical management of cholesteatoma in the Groote Schuur hospital (above13 year age group) and the Red Cross War …
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Downstream Signal Transduction Pathway in Human Middle Ear Cholesteatoma
OBJECTIVES: Human cholesteatoma in the middle ear is characterized by the presence of a keratinized epithelium which is believed to have the hyperproliferative property. The pathogenesis of cholesteatoma including its hyperproliferative characteristic is still unknown. The proliferation and …
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Radiological differences between HIV-positive and HIV-negative children with cholesteatoma
… children are possibly more prone to developing cholesteatoma. Chronic inflammation of the middle ear cleft may be more common in patients with HIV and this may predispose HIV-positive children to developing cholesteatoma. There are no studies that describe the radiological morphology of the …
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Role of downstream signal transduction molecules of congenital middle ear cholesteatoma according to its site of origin
OBJECTIVES: The pathogenesis of congenital cholesteatoma in the middle ear including its hyperproliferative characteristics is still unknown. If the clinical characteristics of congenital middle ear cholesteatoma are different according to the location, we can imagine that its pathogenesis may be …
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Migration of human tympanic epithelium in health and disease
… environment. This condition, described as <i>cholesteatoma*</i>, can, in turn, invade the facial nerve, inner ear and intracranial contents and require surgical intervention which in itself poses some risk to the individual. <br></br><br></br>The probable origins of cholesteatoma have been …
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RegulationofGap Junction Protein,Connexins in Immortalized Human Keratinocytes Cells(HaCaTcells)
… and comprises at least 20 members. Middle ear cholesteatoma is characterized by the presence of a squamous epithelium invading in the middle ear cavity, and is one of the most prevalent forms of otological diseases. The histologic features of cholesteatomas are similar to hyperproliferation and …
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The study of a 3 3-dimentional structure of the congenital anomalous stape stapes compared with normal s stape stapes using Micro Micro-CT
… ossicles and pathologic ossicle destructed by cholesteatoma were reported in our hospital. This study aims to compare the congenital anomalous stapes with normal one and to understand the pathophysiology of congenital stapes anomaly. MATERIALS AND METHOD: The structures of 4 stapeses obtained …
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Functional study of Gap Junctional Intercellular Communication in Human Keratinocyte Cell Line
… been linked to deafness. In human middle ear cholesteatoma, upregulated expression of both connexin 43 and connexin 26 were observed compared to those in normal human skin. In this study, spontaneously immortalized non-tumorigenic and a highly diffenrentiating keratinocyte(HaCaT) cell line was …
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On Pressure Regulation of the Middle Ear
… healthy ears with ventilation tubes (VTs), attic cholesteatoma (AC) and Meniere’s disease (MD) were investigated by measuring the ME pressure directly, continuously and long-term, in combination with ET provocation tests. Pathological conditions were characterised by a negative ME pressure during …
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Charakterisierung des T-Zellinfiltrates in der Cholesteatomperimatrix
In der vorliegenden Arbeit wurden Gefrierschnitte von 28 Cholesteatomen mit unterschiedlichen Entzündungsgraden immunhistochemisch untersucht. Ziel dieser Studie war es, durch immunologische Färbemethoden eine quantitative und qualitative Bestimmung immunkompetenter Zellen im histologischen …