Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"Cholestase"”.
-
Taurocholat-Transport in isolierten proximalen Tubuluszellen der Ratte : Einfluss einer extrahepatischen Cholestase
In the kidneys, the non-protein bound fractions of plasma bile acids are filtered in the glomeruli. The bile acids reaching the tubular fluid are nearly completely reabsorbed by the apical sodium-dependent bile salt transporter (asbt). Hence, with normal conditions, urinary excretion of bile acids …
-
Differentielle Regulation organischer Anionentransporter der Oatp-Familie bei Ethinylöstradiol-induzierter Cholestase der Ratte
Estrogen-mediated cholestasis is an important clinical entity, but its molecular pathophysiology is still not fully understood. The phenomenon of intrahepatic cholestasis under estrogen influence can occur during pregnancy or by taking estrogens for oral anticonception and hormone substitution. …
-
Auswirkungen der obstruktiven Cholestase auf die intestinale Expression von MRP2 bei Ratten und Menschen
Multidrug resistance-associated protein 2 (MRP2), a transporter of organic anions in hepatocytes, renal epithelial cells, and enterocytes, is differentially regulated in liver and kidney during cholestasis, but little is known about its regulation in the intestine. We investigated duodenal protein …
-
Evaluation des geburtshilflichen Managements bei intrahepatischer Schwangerschaftscholestase
Die intrahepatische Schwangerschaftscholestase (ICP) ist die häufigste schwangerschaftsspezifische Lebererkrankung, dessen Ätiologie eine multifaktorielle Genese darstellt. Die Erkrankung geht mit einer Assoziation maternaler und fetaler Risiken einher. Von besonderer Bedeutung für das …