Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Chlorpheniramine maleate"”.
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Using high resolution mass spectrometry to profile impurities in drugs from different sources
… verified. In chapter 4 the organic impurities in chlorpheniramine maleate were investigated using high resolution mass spectrometry in combination with chemometric modelling of the data. Several new impurities of chlorpheniramine maleate were characterised by using MSn and it was demonstrated that …
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A Series of Pharmaceutical Technology Concepts Applied to Pediatric Formulations
… and an anion were utilized in this work (Chlorpheniramine Maleate, Prednisone, Sulfamerazine, and Iodide ion). Each drug molecule was utilized according to its physicochemical properties along with the pediatric patients’ needs. As a result, several pediatric formulations were developed. …
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The production of a lyotropic liquid crystal coated powder precursor through twin screw extrusion.
… granular aggregates. The highly soluble chlorpheniramine maleate loaded in Pluronic F127 solution coated MCC particles prepared through twin screw extrusion was examined to produce the cubic phase (gel) for the development of controlled release formulation and for coating of very fine …
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Developments in Raman spectrometry and intracavity laser absorption spectrometry for quantitative analysis
… study, an HPLC method was devised to quantify chlorpheniramine maleate (the API) in a sample set of more than 280 Chlortrimeton allergy tablets containing a stated API mass of 4 mg. Despite utilising a multi-stage, destructive sample preparation sequence, the average calculated API mass was …
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Design and development of drug delivery systems for immediate and sustained release utilizing hot melt extrusion
… form III. Xylitol exhibited good processability. Chlorpheniramine Maleate (CLPM) and Diltiazem Hydrochloride (DTZ) were used as a model API to design a sustained release pellet formulations utilizing Ethocel<sup>TM</sup> (EC). EC is also studied as matrix former with lipophillic processing aids …
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Preclinical evaluation of dissolvable microarray patches for allergy treatment: key factors governing in vitro and in silico assessment
… MAP design and performance. Two antihistamines—chlorpheniramine maleate (CPM) and loratadine (LOR)—were incorporated into MAP using distinct micromoulding methods (drug solution diffusion vs molten drug) and formulation types (polymer-based vs drug-only). The final formulations, CPM MAP (70 …
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Methods for removing pharmaceuticals from human urine
… was 8 - 44%, with paracetamol and chlorphenamine maleate experiencing the lowest and highest degradation, respectively. Contrary, the range of degradation for the antiretrovirals (ARVs) due to the high pH was 0 - 100%. Abacavir sulfate and nevirapine experienced no degradation, while stavudine, …