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Showing 1 to 3 of 3 for “"Chlorotoxin (CTX)"”.

  1. Reevaluating Chlorotoxin Targets: Insights Into Glioblastoma Cell Migration and Neuropilin-1 Binding

    … and characterize GBM is one such strategy. Chlorotoxin (Ctx), a 36-amino-acid residue polypeptide derived from Leiurus quinquestriatus scorpion venom, has shown selective binding to GBM cells, making it a promising candidate for diagnostic applications and improving tumor visualization. …

    creighton Repository record for Reevaluating Chlorotoxin Targets: Insights Into Glioblastoma Cell Migration and Neuropilin-1 Binding (opens in a new tab)

  2. Engineering M13 Bacteriophage Nanoplatforms for Diagnostic and Therapeutic Applications

    … phage derived particles, (ii) developed a chlorotoxin (CTX) motif on the M13 p3 capsid to enable phage particle crossing of the blood-brain-barrier and homing to glioblastoma cancer cells, and (iii) built ‘inho’ phage derived transgene cassettes for phage gene delivery in mammalian cells. …

    mit Repository record for Engineering M13 Bacteriophage Nanoplatforms for Diagnostic and Therapeutic Applications (opens in a new tab)

  3. The development of targeting nanosystems for the treatment of glioblastoma and neuroblastoma tumours

    Chlorotoxin (CTX) peptide selectively targets glioblastoma multiforme (GB) and neuroblastoma (NB) and has excellent blood-brain barrier permeability. Therefore, CTX is a promising targeting molecule for nanoparticle (NP) based diagnostic and therapeutic applications. Bimetallic gold-platinum …

    western-cape Repository record for The development of targeting nanosystems for the treatment of glioblastoma and neuroblastoma tumours (opens in a new tab)