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Showing 1 to 9 of 9 for “"Chitosan Scaffolds"”.
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Reinforced chitosan-based heart valve scaffold and utility of bone marrow-derived mesenchymal stem cells for cardiovascular tissue engineering
… stem cells (MSCs) and scaffold stiffness. Chitosan is being widely studied for tissue engineering applications due to its biocompatibility and biodegradability. However, its use in load-bearing applications is limited due to moderate to low mechanical properties. In this study, we …
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3D scaffolds for tissue engineering produced by microfabrication technology
… 3-dimensional (3-D) regular and ordered scaffolds for tissue engineering applications. With these techniques, good architecture reproducibility as well as porosity control of the structure can be obtained. This work dealt with the fabrication of tissue engineering scaffolds with regular …
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Oxygen Transport, Shear Stress, And Metabolism In Perfused Hepatocyte-Seeded Scaffolds With Radial Pore Architecture: Experimental And Computational Analyses
… and viability while cultured in bulk 3D chitosan scaffolds and perfusion bioreactor systems. Cylindrical chitosan scaffolds with radial directed pore structures were fabricated by a thermal gradient directed from the center to the periphery. Capillary-like direct oxygenation was …
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Chitosan fibrous scaffolds for cartilage tissue engineering
The biocompatibility of chitosan and its similarity with glycosaminoglycans make it attractive for cartilage engineering despite its limited cell adhesion properties. Structural and chemical characteristics of chitosan scaffolds may be improved for cartilage engineering application. We planned to …
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Development of 3-d liver model for drug screening applications
… a three-dimensional (3-D) liver model using chitosan-based nanofiber scaffolds and co-culture system (adult rat hepatocytes and 3T3-J2 fibroblasts) to mimic the natural liver and to justify its application for in vitro drug screening. Chitosan nanofiber scaffolds were fabricated by …
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Biofuel Cell Anode for NAD-Dependent Enzymes
… research; based on the combination of porous chitosan scaffolds and multi-walled carbon nanotubes that stabilizes enzymes while enabling mass transport of fuels and providing electrical conductivity. This research ultimately introduces a common technology platform for NADH re-oxidation in a …
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Development of a biodegradable biopolymer from renewable natural resources suitable for additive manufacturing and bone tissue engineering
Bone tissue engineering scaffolds fabricated by additive manufacturing can offer an alternative treatment option to currently used bone graft methodologies. Chitosan, a biocompatible and biodegradable naturally derived polymer, offers great promise as a biomaterial for tissue engineering …
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Development Of Scaffold Architectures And Heterotypic Cell Systems For Hepatocyte Transplantation
… we first compared two designs of highly porous chitosan-heparin scaffolds seeded with hepatocytes in dynamic perfusion bioreactor systems. The aim was to promote cell seeding efficiency by effectively entrapping 100 million hepatocytes at high density. We found that scaffolds with radially …