Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Chiral drugs"”.
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Stereoselective metabolism of verapamil and four other chiral drugs by cDNA expressed CYP450's.
… metabolism of verapamil and four other chiral drugs by cDNA expressed CYP450's.
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Auxiliares quirales derivados de carbohidratos: Nuevas aplicaciones
… much attention in recent years as a source of chirality for the synthesis of chiral drugs and natural products, because of their variety, cheapness and synthetical affordability. In this context, this PhD Thesis describes new methodologies based on carbohydrate derivatives as chiral auxiliaries …
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An investigation into the use of B-cyclodextrins as additives to effect enantiomeric separation by reversed phase HPLC.
The occurrence of chirality in organic molecules and its significance for the clinical effects of drug molecules is reviewed. A need is established for suitable methods, both analytical and preparative for the separation of enantiomers. The present range of analytical methods used for …
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Studies on new approaches of chiral discrimination for chiral analysis by regression modeling of spectral data.
Two new approaches of chiral discrimination for enantiomeric composition analysis using isotropic spectroscopic techniques and multivariate regression modeling were investigated. This is in view of the urgent need for rapid and improved strategies for chiral analysis due to the rising preference …
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Multifaceted computational modelling in pharmaceutical research and development
… carboplatin, and gemcitabine anticancer drugs and also drug combinations such as doxorubicin with carboplatin, paclitaxel with gemcitabine and carboplatin employing NUIG-4 metal-organic framework as drug delivery agents. In this chapter, the comprehensive understanding of molecular …