Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Chimaera"”.
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The Impact of Fishing on Populations of Deep-water Chondrichthyan Fishes of the Northeast Atlantic
… coelolepis, Centrophorus squamosus and Chimaera monstrosa by decade and gear type, suggesting that these species may be some of the most vulnerable deep-water chondrichthyans when faced with intensive commercial fishing. Nevertheless data used in multivariate models were fragmentary and …
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The United States and the State of Israel: a Critical Examination of U.S.-Israel Relations Since 1981
… goals in the Middle East, including the chimaera of peace. The policies of the Bush, Clinton and Rabin administrations have demonstrated a willingness to risk Israeli security in the pursuit of amorphous Arab-Israeli peace. The danger of these policies is that through the concession of …
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Discovery and design of novel bioactive peptides from amphibian skin secretion
… 5, the idea of a modified hybrid peptide (chimaera) was presented. The N terminus of different families of AMPs was selected for fusion with the fixed C terminus, and the changes in functional activity and toxicity were observed to identify the hybrid peptides with a relatively high …
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Computational reconstruction of mouse development using single cell transcriptomics
… to the system using mouse embryonic chimaera KO models are included. The analysis of haemato-endothelial lineages, presents a detailed reconstruction of the in vivo developmental process not reached by previous studies with single cell transcripomics. Lastly, predicted cell fates are …
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Molecular Basis of Mechanosensitivity
… swelling provided additional support that Paddle Chimaera and Kv2.1 are indeed mechanosensitive in cellular contexts. Given the close structural similarity between voltage gated potassium channels and other ion channel families, I extended these studies to include sodium and calcium selective …
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Single-cell genomics in rabbit and mouse elucidate eutherian embryonic development
… (CRISPR)-mediated knock out cell lines. Using a chimaera model system where knock-out (KO) cells are injected into wild-type (WT) host blastocysts, we can understand the cell-autonomous role that each TF plays. In conclusion, studying single-cell transcriptomics unveils the molecular profiles …
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Generation and characterization of HIV-1 subtype C candidate vaccines that will induce high titre antibody responses to HIV-1 envelope glycoprotein
… of Env on VLPs and the plasma membrane, two Env chimaeras were made replacing parts of gp41 with the corresponding elements of influenza A H5 haemagglutinin (HA2) (Env:HA2 chimaeras). Increased Env spike density was observed in a previous study using this strategy for the gp41 transmembrane …
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Mesoderm diversification during mouse embryonic development
… regulator $\textit{Tal1}$ using mouse embryonic chimaeras and reveal that endothelial cells are transcriptionally aberrant at early organogenesis and express genes characteristic of other mesodermal lineages. Although single-cell transcriptomics unveils the molecular programs defining each cell …