Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 18 of 18 for “"Childhood Cancer Survivors"”.
-
Infrastructure Development For Personalized Risk Prediction to Reduce Cardiovascular Disease In Childhood Cancer Survivors
<p>Although childhood cancer survivors have lengthy life expectancies, they run the risk of experiencing long-term health issues as a result of their treatment. The most frequent non-cancerous cause of morbidity and mortality for these survivors is cardiac disease. Radiation therapy (RT) has been …
-
Back to School, Back to Normal? Exploring the Lived Experiences of Childhood Cancer Survivors and their Families Throughout the School Re-Entry Process
… investigated parent and child perspectives of childhood cancer survivors' return to school. Four specific areas were examined including cognitive and academic concerns, social issues, perceived support, and the impact on siblings. Participants consisted of parents and childhood cancer survivors …
-
Survivor guilt and posttraumatic stress among young adult survivors of childhood cancer
<p>Childhood cancer survivors are at risk for a variety of adverse physical and mental health outcomes. Posttraumatic stress disorder (PTSD) occurs in a small, but notable, minority of childhood cancer survivors. Little is known about modifiable factors that may increase the risk of developing PTSD …
-
Risk of Subsequent Neoplasms During the Fifth and Sixth Decades of Life in the Childhood Cancer Survivor Study Cohort
Childhood cancer survivors are at increased risk for subsequent neoplasms (SNs), but the incidence beyond age 40 and associations with therapeutic exposures have not been well- described. Among 14,364 childhood cancer survivors diagnosed between 1970 and 1986, 3,171 had an attained age ≥40 years at …
-
Risk and Risk Factors For Colorectal Subsequent Malignancies In Survivors of Childhood Cancer: A Report From The Childhood Cancer Survivor Study
<p>Survivors of childhood cancer are at risk for colorectal subsequent malignant neoplasms (SMNs); notably, these cancers are amenable to screening. To identify at-risk survivors that may benefit from early screening, descriptive and risk factor analyses were performed to ascertain risk factors for …
-
QUALITY OF LIFE IN SURVIVORS OF CHILDHOOD CANCER: A GROUNDED THEORY APPROACH
… study was to understand the processes survivors of childhood cancer go through with regard to their quality of life (QOL), how they define QOL, and what factors facilitate and hinder good QOL. Eight survivors participated in semi-structured interviews. Strauss and Corbin's (1990) …
-
Parent-child differences in psychological distress following childhood cancer treatment
<p>While the prognosis for pediatric cancer is improving, survivorship is accompanied by a number of potential long-term consequences. While not all childhood cancer survivors (CCS) and their parents experience psychological distress during survivorship, research does indicate that at least some do …
-
Reconstructing experience of childhood cancer: a narrative inquiry
Many childhood cancer survivors experience long-term effects from their illness long after their treatments are over. In order to more fully understand the impact these effects have on a young person’s life, there is a need for more patient illness narratives. Using Connelly and Clandinin’s …
-
Doxorubicin-Induced Cardiotoxicity Is Mediated By Neutrophils Through Release of Neutrophil Elastase
… agents that is used for the treatment of childhood cancer. Unfortunately Dox treatment can cause damage to the heart. Indeed, childhood cancer survivors are at a higher risk of developing a cardiovascular disease at an earlier age. The mechanisms by which Dox causes acute and late …
-
Incidence and Clinical Relevance of Abnormal Complete Blood Counts in Survivors of Childhood Cancer
… blood counts (CBCs) obtained during follow-up of childhood cancer survivors. METHODS: A retrospective cohort study was conducted on 193 survivors, diagnosed between 1970-1986, who have been followed in our center's After Cancer Experience Program and are participants in the Childhood Cancer …
-
The pre-clinical evolution of haematological malignancies
Cancer-associated somatic mutations frequently drive clonal expansions in normal ageing tissues. However, the factors governing whether pre-cancerous cells transform into cancer are poorly understood, hindering identification of clones that are clinically significant rather than benign sequelae of …
-
Advancement of A 3D Computational Phantom and Its Age Scaling Methodologies For Retrospective Dose Reconstruction Studies
… for retrospective dose reconstruction studies of childhood cancer survivors (CCS) treated with 2D historic radiotherapy (RT). However, our phantom and its age scaling functions (ASF) must be updated so that it can be used in studies that include survivors treated with contemporary RT. We aimed to …
-
Neurocognitive outcomes in children experiencing seizures during treatment for acute lymphoblastic leukemia
… literature for cognitive late effects among childhood cancer survivors, yet little empirical information is known regarding specific neurocognitive outcomes of children who experience seizures while treated for acute lymphoblastic leukemia. This study examined prevalence of on-protocol …
-
Hereditary and inborn etiology of pediatric cancer
The etiology of childhood cancer remains largely elusive. In rare cases, genetic mutations and environmental exposures such as radiation are known causes. For the vast majority of childhood cancer patients, there is no known cause for their disease. With an increasing number of childhood cancer …
-
Impact of chemotherapy on the release and function of extracellular vesicles in the pre-pubertal testis
INTRODUCTION: Childhood cancer affects nearly 2,000 children in the UK each year and encompasses a range of pathologies. The incidence of childhood cancer is rising, and the peak age of onset occurs between 0 - 4 years old. Despite more children being diagnosed with cancer year after year, advances …
-
Resilience and Quality of Life in Taiwanese Survivors of Childhood Cancer
Survivors of childhood cancer are at risk to develop physiologic-psychosocial complications that affect their quality of life. This study explored how the independent variables of illness-related risk (ILLRK), individual risks (IRK), protective factors (PF) and resilience (RS) affected the …