Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 57 for “"Chikungunya"”.
-
The spread and control of dengue and chikungunya viruses
Mosquito-borne viruses such as dengue and chikungunya viruses continue to cause a substantial burden on public health globally. After decades with few tools to tackle the spread of these viruses, new interventions are becoming available. The release of Wolbachia infected mosquitoes has been shown …
-
Experimental and computational study of the mechanics of chikungunya
… and computationally the mechanical properties of chikungunya virus to enable mechanobiological investigations of interactions between the chikungunya virus, and other enveloped viruses, and host cells involved in the infection process. The chikungunya virus strain used was the S27-African …
-
Production and Testing of a Novel Live-Attenuated Chikungunya Vaccine
… and testing of a novel live-attenuated chikungunya virus (CHIKV) vaccine. To this end, multiple strategies were adapted from the IRES-based vaccine strategy first employed with VEEV vaccine strain, TC-83. The first strategy, CHIKV/IRESv1, was highly stable during cell culture passages in …
-
The spread of Nipah and chikungunya viruses: implications for control
… a substantial burden on public health. Nipah and chikungunya have been identified as two emerging viruses that pose a significant threat with pandemic potential. This has led to considerable investment in the development of vaccines against the two pathogens, especially by the Coalition for …
-
A Role for Interferon Stimulated Gene-15 (ISG15) During Chikungunya Virus Infection
… for Interferon Stimulated Gene-15: ISG15) During Chikungunya Virus Infection</p><p>By</p><p>Scott William Werneke</p><p>Doctor of Philosophy in Biology and Biomedical Science</p><p>(Immunology)</p><p>Washington University in St. Louis, 2013</p><p>Professor Deborah J. Lenschow, …
-
Translational Frontiers for Chikungunya Virus: New World Epidemic, New Strains, New Therapeutic Targets
Chikungunya virus (CHIKV) infection results in chikungunya fever (CHIKF), marked by sudden onset of high fever, rash, and debilitating polyarthritis and polyarthralgia, which can last for months to years. Despite the severe morbidity and impact on disability adjusted life-years, an FDA-approved …
-
Development of Rapid Lateral-flow Immunochromatographic Test for the Diagnosis of Chikungunya Virus Infection
BACKGROUND/AIMS: Chikungunya (CHIK) virus is a mosquito-transmitted Alphavirus belonging to family Togaviridae that causes a number of outbreaks in Africa, India, and Southeast Asia with high morbidity. The major clinical symptoms resulting from CHIK virus infection are high fever, arthralgia, …
-
Evaluation of Chikungunya Virus Infectious Events in Aedes Albopictus LR and Aedes Aegypti WE Mosquito Vectors
… and transmission are still not fully understood. Chikungunya virus (CHIKV) is an alphavirus transmitted by Aedes albopictus and Aedes aegypti mosquitoes in tropical areas of Africa, Asia, and the islands of the Indian Ocean. In 2007 and 2009, CHIKV was transmitted outside these tropical areas to …
-
Characterization of the role of the innate immune system in the pathogenesis of chikungunya virus in mice
Chikungunya virus (CHIKV) is an alphavirus which causes a febrile illness in people that can induce a persistent and recurrent arthralgia. Recent outbreaks of CHIKV in tropical regions have caused millions of people debilitating illness. With no specific vaccine or anti-viral treatment, the …
-
γδ T CELLS MEDIATE PROTECTIVE IMMUNE RESPONSES INDUCED BY EILV/CHIKV, A CHIMERA VACCINE CANDIDATE, AGAINST CHIKUNGUNYA INFECTION
Chikungunya virus (CHIKV) is a re-emerging virus that causes acute chikungunya fever, often accompanied by severe and persistent arthralgia, known as chronic CHIKV infection (CHIKD). Development of safe and effective vaccines against CHIKV infection and disease remains a high priority. Eilat virus, …
-
Adaptation of Chikungunya virus to Aedes albopictus mosquitoes: The role of mutations in the E1 AND E2 glycoproteins
Chikungunya virus (CHIKV) is a positive sense single-stranded RNA virus in the family Togaviridae that between 2005 and 2007 caused its largest outbreak/epidemic in documented history, affecting parts of Africa, the Indian Ocean islands, India, and Europe. An unusual feature of this epidemic was …
-
The Expression of Chikungunya Virus Envelope 2 Glycoprotein Variants in Nicotiana benthamiana for the Development of a Diagnostic Reagent
Chikungunya fever is a non-fatal but highly debilitating disease that affects primates, birds and humans. The causative agent is the chikungunya virus (CHIKV), an arbovirus of the Alphavirus genus. CHIKV is responsible for the largest epidemic recorded for an Alphavirus, infecting an estimated 1.4 …
-
Pruebas de laboratorio serológicas y hematológicas para el diagnóstico presuntivo de Chikungunya y/o dengue en usuarios menores de 10 años que son ingresados en el servicio de pediatría, Hospital Nacional San Juan de Dios del municipio y departamento de San miguel, julio de 2016
… Tanto la enfermedad del dengue como la del Chikungunya cursan con síntomas clínicos similares al inicio de la enfermedad es por ello que el objetivo de la investigación fue establecer mediante pruebas de laboratorio Serológicas y Hematológicas un diagnóstico presuntivo de Chikungunya y/o …
-
The use of insect cells to identify potent and selective inhibitors of the replication of the Dengue and Chikungunya viruses and unravel their molecular mechanism of action
Dengue and Chikungunya viruses cause the most important arthropod-borne viral infections for humans. These viruses are predominant in tropical and subtropical regions. In addition, these viruses are predominant in tropical and subtropical regions. Dengue mortality rate is around 1.2 to 3.5% and …
-
Freirean Codes: A Transformative Educational Tool for Community Empowerment and Arboviral Control in Kenya
<p>Dengue and chikungunya fever are two of the fastest spreading tropical diseases globally. There are 390 million dengue infections per year globally, and 65 million cases in Africa. In East Africa, Kenya and Tanzania have suffered outbreaks of these diseases. Dengue fever is transmitted by the …
-
Perceptions of measures to control Aedes mosquitoes and mosquito-borne diseases in Costa Rica
… aegypti is the most competent vector of dengue, chikungunya, Zika, and yellow fever. With up to 400 million cases globally each year, dengue fever is the fastest growing vector-borne disease in the world, and it has become an increasingly significant risk to global health. In the Western …
-
Análise de receptores tool-like e citocinas envolvidas na susceptibilidade à infecções virais
… ocasionadas pelos vírus da Dengue (DENV), Chikungunya (CHIKV) e Zika (ZIKV). A infecção pelo CHIKV causou grande impacto a saúde pública devido a presença de sintomas altamente debilitantes como, inflamações nas articulações que podem durar meses ou anos. A inflamação induzida pela infecção …
-
Intersecting Threats: Exploring Obesity's Impact on Viral Pathogenesis and Transmission
… viruses like West Nile Virus (WNV), chikungunya virus (CHIKV) and Mayaro virus (MAYV) and reduce the vaccine efficacy for influenza and SARS-CoV-2. Obesity is associated with a chronic state of inflammation and dysregulated immune response which has been proposed to be one of the …
-
Vector-borne Disease Risk Assessment in Times of Climate Change: The Ecology of Vectors and Pathogens
… competent vector of pathogens such as dengue and chikungunya, among others. By means of correlative species distribution models, suitable European regions are identified. The comparison of published results for various Aedes albopictus risk models, including the aforementioned, shows that beside …
-
Aptamer-based sequence verification platform for rapid multiplexed detection of viral RNA targets
… they are often misdiagnosed with, like Zika and Chikungunya viruses. With these platforms, we demonstrate both a quantitative and qualitative distinguishment of up to four mosquito borne pathogenic RNA targets at once in a single multiplexed detection platform.
Page 1 of 3