Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Chemotherapeutic Response"”.
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Identification and Characterization of Modulators of Chemotherapeutic Response in Mouse Models of Cancer
Chemotherapeutic drug resistance is a major cause of cancer treatment failure. While much attention has been focused on the genetics of tumor development, less is known about the genetic determinants of therapeutic outcome. As a central focus of my graduate work, I have employed pool-based …
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Rev7 is a novel regulator of chemotherapeutic response in drug-resistant lung cancer
Most malignant cancers are treated with chemotherapeutic agents that target and damage cellular DNA While genotoxic chemotherapies have proven to be highly effective agents for cancer therapy, it is well known that intrinsic and acquired cancer drug resistance is a problem that severely limits the …
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Dynamic Contrast-Enhanced MRI and Diffusion-Weighted MRI for the Diagnosis of Bladder Cancer
… it is important to predict a patient as a chemotherapeutic responder or non-responder to both maximize the patient benefit from chemotherapy and avoid unnecessary delay of cystectomy. However, these clinical needs in bladder cancer management are still unmet in clinical tests, cystoscopy, …
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Investigation of cellular microenvironments and heterogeneity with biodynamic imaging
… to accurately assessing the effectiveness of chemotherapeutic agents in combatting cancer. Though many three-dimensional (3D) culture models exist, conventional <em>in vitro</em> assays continue to use two-dimensional (2D) cultures because of the difficulty in imaging through deep tissue. 3D …