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Showing 1 to 8 of 8 for “"Chemoreflex"”.
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Longterm peripheral baroreflex and chemoreflex function after bilateral eversion carotid endarterectomy
… the e-CEA on arterial baroreflex and peripheral chemoreflex function in humans. Methods A retrospective review was conducted on a prospectively compiled computerized database of 3128 CEAs performed on 2617 patients at our Center between January 2001 and March 2006. During this period, a total of …
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Mechanisms Mediating Modulation Of The Cardiopulmonary Chemoreflex Control Of Regional Sympathetic Outputs By Adenosine A1 And A2a Receptors In The Nts
… sympathetic nerve activity. Cardiopulmonary chemoreflex (CCR), also known as Bezold-Jarisch reflex, triggered by various chemicals inhaled or released during myocardial ischemia, may have beneficial effects when it decreases afterload and heart rate thus decreasing oxygen demand. However, …
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Neurons projecting to the paraventricular nucleus of the hypothalamus are activated and contribute to cardiorespiratory responses to systemic acute hypoxia
… of these two pathways to peripheral and central chemoreflex function. We found that lesion of PVN-projecting catecholaminergic cells significantly attenuated ventilatory responses to hypoxia and hypercapnia. Data indicate that catecholamine neurons projecting to the PVN are critical for both …
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Sympathetic control of carotid body excitability in hypertension: A preclinical study
… is mediated by its sympathetic innervation. Chemoreflex was activated (NaCN 50-100 μL, 0.04%) in Wistar and SH rats in situ before and after: 1) electrical stimulation (ES; 30 Hz, 2 ms, 10 V) of the superior cervical ganglion (SCG), which innervates the carotid body; 2) unilateral resection …
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Identifying evolving multivariate dynamics in individual and cohort time series, with application to physiological control systems
… identification and stability of the respiratory chemoreflex system, which is key to the pathogenesis of sleep-induced periodic breathing and apnea. Using data from both an animal model of periodic breathing, as well as human recordings from clinical sleep studies, we demonstrate that model-based …
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Unstable Ventilatory Control During Sleep After High Spinal Cord Injury: The Contribution Of Chemosensitivity And Hypoventilation
… by upper airway mechanics and a high peripheral chemoreflex response to O2 and CO2. Sleep onset hypoventilation and high peripheral chemoresponsiveness may contribute to the development SDB in the SCI population.</p>
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Activation of 5-HT1A Receptors in the Nucleus Tractus Solitarius Facilitate Ventilatory Responses to Hypoxic Hypercapnia and Promote Sympathetic Recovery Following Hypotensive Hemorrhage
… 5-HT<sub>1A</sub> receptors which facilitate chemoreflex responses. We utilized viral-mediated knockdown of the rat 5-HT<sub>1A</sub> receptor in the caudal NTS (cNTS) to examine the role of 5-HT<sub>1A</sub> receptors on compensation following hemorrhage and ventilatory responses to …
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Hindbrain Serotonin Neurons Activate 5-HT1A Receptors in the Nucleus Tractus Solitarius (NTS) to Modulate Sympathetic and Ventilatory Recovery Following Hypotensive Hemorrhage
<p>Trauma is the leading cause of death of young people in the United States. Most such deaths result either from the initial blood loss or from secondary reperfusion injury following resuscitation.</p><p>Currently, the standard treatments for hypovolemic shock include volume resuscitation and …