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Showing 1 to 3 of 3 for “"Chemical penetration enhancers"”.

  1. QSAR modeling of chemical penetration enhancers using novel replacement algorithms

    … 500 Da, are suitable to cross the skin barrier. Chemical Penetration Enhancers (CPEs) are used to promote the absorption of solutes across the dermal layers. In this investigation, a Quantitative Structure-Activity Relationship (QSAR) model is applied to relate chemical penetration enhancer …

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  2. Chemical penetration enhancers and in situ-forming reservoirs for trans-tympanic drug delivery : progress toward improved treatment of Otitis media

    … A hydrogel that includes potentially synergistic chemical penetration enhancer (CPE) combinations and an antimicrobial sufficiently increases antimicrobial flux such that therapeutic levels can traverse the tympanic membrane (TM) within 12 hours, in vitro. We compare excised chinchilla TMs treated …

    mit Repository record for Chemical penetration enhancers and in situ-forming reservoirs for trans-tympanic drug delivery : progress toward improved treatment of Otitis media (opens in a new tab)

  3. Role of cavitation, surfactants, and their synergism in transdermal sonophoresis

    … mechanism that causes synergism between LFS and chemical penetration enhancers (CPEs), iii) the interactions between traditional and non-traditional surfactants in LFS skin treatments, and iv) the effects of LFS and LFS/CPEs on skin structural perturbation. In the first study of this thesis, the …

    mit Repository record for Role of cavitation, surfactants, and their synergism in transdermal sonophoresis (opens in a new tab)