Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"Cerebrovascular reactivity"”.
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Continuous Multi-Modal Monitoring of Cerebrovascular Reactivity in Adult Traumatic Brain Injury
… global outcome. Continuously updating indices of cerebrovascular reactivity provide a convenient and continuous metric regarding an individual patients’ autoregulatory status. To date, the vast majority of the literature has focused on pressure reactivity index (PRx), which has emerged as the …
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Monitoring of cerebral oxygenation, cerebrovascular reactivity and circulatory function in preterm infants
Monitoring of cerebral oxygenation, cerebrovascular reactivity and circulatory function in preterm infants Brain injury in the preterm infant is associated with death and lifelong disability. Cerebral hypoxia and fluctuations in cerebral blood flow in the first two days of life have been implicated …
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Exploring The Translational Clinical Value of Cerebrovascular Reactivity Assessments by Diffuse Correlation Spectroscopy
Cerebrovascular reactivity (CVR), i.e., the ability of cerebral vasculature to dilate or constrict in response to vasoactive stimuli, is a biomarker of vascular health and CVR quantification is considered an unmet clinical need. However, the value of addressing this unmet need is not clear. This …
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Characterizing the effects of repetitive head trauma in female soccer athletes for prevention of mild traumatic brain injury
… with head impact monitoring to assess changes in cerebrovascular reactivity and resting state functional connectivity in female soccer athletes and to test whether the observed changes can be attributed to the cumulative mechanical load experienced by female athletes participating in high school …
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Investigating the protective role of heart rate variability on the effects of aging on cerebrovascular function as estimated by optical pulse parameters
… of a reduced vagal role resulting in reduced cerebrovascular reactivity and, indirectly, brain tissue damage. Here we investigate these relationships using a novel approach to studying cerebrovascular reactivity based on single-trial measures of the cerebral arterial pulse measured with …
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The impact of ischaemic preconditioning on cerebrovascular function in healthy individuals.
… impact of RIPC on cerebral blood flow (CBF) or cerebrovascular function. The overall aim of this thesis was to assess, in healthy individuals, the impact of bilateral arm RIPC or SHAM on resting CBF, cerebrovascular reactivity, cerebral autoregulation, and autoregulation during hypercapnia. …
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Neurovascular implications of life-long exposure to contact in rugby union; the link to cognition
… thesis sought to: 1) determine the molecular, cerebrovascular and cognitive signatures of professional rugby union players over a single season, stratified by frequency of contact events, playing position and concussion risk, and 2) determine the chronic molecular, cerebrovascular and cognitive …
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Understanding the role of cerebrovascular health in cognitive aging: a multi-modal noninvasive human neuroimaging approach
… Thus, it is critical to determine the effect of cerebrovascular health on cognition and the mediators of cerebrovascular health across the lifespan. Since aerobic fitness is known to alleviate both cognitive and volumetric losses in the brain, it is important to investigate some of the possible …
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Endothelin-1 and Hypoxic Vascular Remodeling in Ovine Fetal Cerebral Arteries
… that chronic hypoxia altered ovine fetal cerebrovascular reactivity to ET-1 but not plasma ET-1 levels or ETA receptor cerebrovascular </p> <p>expression. However, chronic hypoxia enhances ET-1-induced contractility in an ETAdependent manner in Middle Cerebral Arteries (MCAs). ET-1 also …
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Prevention of stroke: risk stratification and targeted and novel therapies
… ability to reduce the referral of those without cerebrovascular disease to busy TIA clinics. The score was developed on data from 3216 patients and included 9 clinically useful predictive variables. After adjustment to reflect the greater seriousness of missing true TIA patients, 97% of TIA and …
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Parkinson's disease and degenerative parkinsonism: relationship between clinical and neurobiological aspects
Il neurovascula coupling indica il processo mediante il quale l unità neuro vascolare modula la complessa relazione tra attività neuronale, fattori emodinamici e segnali intracellulari. Recenti studi individuano la possibile associazione tra alterazioni dell emodinamica cerebrale e il decadimento …
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Cerebrovascular influence on brain and cognitive aging
A dysfunctional cerebrovascular system can result in severe adverse effects on brain health and cognitive aging. Recently, Fabiani et al., (2014) introduced a novel non-invasive approach of quantifying cerebrovascular health using diffuse optical imaging in a sample of older adults. This method is …
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Novel Interventions to Improve Cerebral and Peripheral Vascular Function
… Impairments to cerebral blood flow (CBF) and cerebrovascular function result in increased risk of cognitive impairment, vascular dementia and stroke. Identifying interventions that can attenuate the age-related decline in CBF and enhance cerebrovascular function are essential, especially in …
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HIITing the Brain with Exercise; the Effect of High-Intensity Interval Training on Cerebrovascular and Cognitive Function
… improved musculoskeletal, cardiopulmonary and cerebrovascular function. However, the time commitment associated with MICT is a common barrier to participation. High-intensity interval training (HIIT) has since emerged as a more time-efficient mode of exercise that can promote similar, if not …
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Peripheral and Cerebrovascular Function during the Female Lifespan
… via middle cerebral artery velocity (MCAv), cerebrovascular reactivity (CBV-R) and cerebral autoregulation. Peripheral vascular function (brachial and femoral artery endothelial function via flow mediated dilation (FMD)) and structure (brachial (b), femoral (f) and carotid (c) intima-media …
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The influence of acute, chronic and lifelong hypoxia on the functional and structural integrity of the neurovascular unit
… oxygen<br/>CSF – Cerebrospinal fluid<br/>CVR – Cerebrovascular reactivity<br/>DO<sub>2</sub> – Delivery of oxygen<br/>EET – epoxyeicosatrienoic acid<br/>eNOS – Endothelial nitric oxide synthase<br/>F<sub>I</sub>CO<sub>2</sub> – Fraction of inspired carbon dioxide<br/>F<sub>I</sub>O<sub>2</sub>– …