Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Cerebrovascular Pathology"”.
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Modulation of Alzheimer’s Disease Pathology by Collagen-Induced Rheumatoid Arthritis in APP/PS1 Mice
… plaque formation, microglial activation, and cerebrovascular pathology in the cortex and hippocampus of the double transgenic APP/PS1 mouse model for AD. Wild-type or APP/PS1 mice that received type II collagen (CII) in complete Freund’s adjuvant (CFA) at presymptomatic stage (2 months) or …
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Characterization of The Vascular Pathology In The Acta2 R258C Mouse Model and Cerebrovascular Characterization of The Acta2 Null Mouse
… <em>ACTA2</em> are described as moyamoya-like cerebrovascular incidents characterized by distal occlusion of the internal carotid artery, stenosis of arteries in the Circle of Willis, and straightening of cerebral arteries. Patient samples are scarcely available for analysis, and the few …
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On the neurobiology of apathy and depression in cerebral small vessel disease
Cerebral small vessel disease (SVD) is a cerebrovascular pathology that affects the small vessels of the brain, resulting in heterogeneous brain tissue changes. These can lead to neuropsychiatric symptoms such as apathy, a loss of motivation, and depression, which is characterised by low mood and a …
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Visualization and analysis of large medical image collections using pipelines
… in stroke patients. Our study of this cerebrovascular pathology consists of three main components: accurate registration to enable data fusion and population analysis, segmentation to automatically delineate pathology from the images, and statistical analysis to extract clinical insight …
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Cerebrovascular and Neuronal Cellular Consequences of Amyloid-β Induced Nuclear Factor-κB Activation
… AD patients also display varying degrees of cerebrovascular pathology including the deposition of Aβ within vessel walls known as cerebral amyloid angiopathy (CAA). The prevalence of CAA and of dementia caused directly by vascular damage supports the idea that cognitive impairment arises from …
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Cerebral Amyloid Angiopathy-Causing Beta-Amyloid Variants Have Altered Effects on the Clotting System
… underlying CAA formation and CAA-induced cerebrovascular pathologies, including intracerebral hemorrhage (ICH) is unclear. Hereditary cerebral amyloid angiopathy (HCAA) is a rare familial form of CAA in which mutations within the Aβ peptide cause an increase in vascular deposits. Since the …
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Cholinesterase Inhibitors and Neuropathology of Cerebrovascular Disease and Other Dementias in Patients with Alzheimer’s Disease: A Study of NACC Autopsy and Medical History Data, 2005 – 2017
… objective was to assess the impact of ChEI on cerebrovascular or neurodegenerative pathologies in patients with AD. Using the National Alzheimer’s Coordinating Center database, we identified 2245 individuals with at least two annual visits where medications were recorded, an etiologic clinical …