Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Cerebrovascular Diseases"”.
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Multiparametric Estimation of Brain Hemodynamics with MR Fingerprinting ASL
… cerebral physiology and clinical application in cerebrovascular diseases. Arterial Spin Labeling (ASL) MRI technique is capable of estimating cerebral blood flow (CBF) without radioactive tracer or contrast agent. However, the signal from ASL is affected by multiple parameters in the kinetic …
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A dissection and angiographic study of anatomical variations in the anterior communicating artery complex in a South African sample
… and aneurysm development has been reported. Cerebrovascular diseases play a significant role in the causes of morbidity in South Africa. South African data in this area of research is currently lacking and thus more knowledge is needed. This study aims to report the prevalence of variations …
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Inherited risk for common disease
… few gene-disease associations for common diseases. The explanation has been offered that complex modes of inheritance govern risk for cancers, cardiovascular and cerebrovascular diseases, and diabetes. Such studies, however, depended on the untested assumption of monoallelic risk. My …
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Loneliness as a risk factor for mortality and morbidity
… health, mortality, and fatalities from specific diseases. A key hypothesis is that loneliness as a health problem hinges on its persistence over time. This hypothesis is also tested by examining the reliability of the loneliness measure across the full 34 years of the survey. A second test is to …
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Hemodynamic regulation of blood-brain barrier phenotype: A cooperative effort linking adherens and tight junction complexes
… barrier dysfunction are established features of cerebrovascular diseases (e.g. stroke) manifesting compromised blood flow, allowing us to hypothesize a pivotal regulatory link between BBB phenotype and flow-associated shear stress. In this regard, our research has demonstrated that exposure of …
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The influence of size and progression of Intra-cerebral Hematoma on the Lateral Ventricles
<p>Cerebrovascular diseases like intra cerebral hemorrhage are quite deadly and may disturb functioning of the brain, expanding and resulting in formation of an intra cerebral hematoma(ICH). It is imperative to comprehend how hematoma and its expansion inside the brain endangers human life. One of …
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Endovascular Optical Coherence Tomography Imaging in Cerebrovascular Disease
… on the diagnosis and treatment of vascular diseases of the central nervous system. The appeal of treating vascular diseases through minimally invasive techniques without the need for open surgery has led to continued technological innovation and device development. Endovascular optical …
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Novel Machine Learning Algorithms for Personalized Medicine and Insurance
… analytics in the context of cardiovascular and cerebrovascular diseases. To propel the adoption of these methodologies, we lay the foundations in the area of algorithmic insurance, proposing a quantitative framework to estimate the litigation risk of machine learning models. This work emphasizes …
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Towards wearable stress measurement
… risks, including cardiovascular and cerebrovascular diseases, diabetes, and immune dysregulation. An important step in managing stress, before it becomes chronic, is recognizing precisely when and where it occurs. This thesis creates and evaluates new methods to improve the …
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Parâmetros assistenciais e procedimentos do sistema estomatognático e dos distúrbios da comunicação humana em um centro de terapia intensiva neurológico
… ICU, this is due to the predominance of cerebrovascular diseases. There are discrepancies between the number of procedures aimed at assessing, diagnosing and rehabilitating these users. There is also a high prevalence of SE and DCH disorders in these hospital environments.
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The Therapeutic Role of LM11A-31 (a p75NTR Modulator) in the Outcome of Ischemic Stroke and HIV-1 Pathogenesis
… individuals are more suspectable to develop cerebrovascular diseases, including ischemic stroke, than non-infected individuals. Due to the limited ability of antiretroviral drugs to cross the BBB and achieve therapeutic concentration, LM11A-31 is a promising treatment for reducing HIV-1 …
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THE EFFECTS OF MYOCARDIAL INFARCTION ON NEUROINFLAMMATION: FOCUS ON THE ROLE OF EXTRACELLULAR VESICLES
Cardiovascular diseases (CVDs) are considered the leading cause of premature death globally, with an estimated 17 million deaths yearly, according to the World Health Organization (WHO). CVDs include a collection of diseases, most importantly cardiac ischemia. Complications following cardiac …
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The effects of sitting on cerebrovascular and cognitive function
… (PA) levels. Despite associations between SB and cerebrovascular disease, little research has assessed the influence of SB on cerebrovascular function, comprising cerebral blood flow (CBF), cerebral autoregulation (CA) and cerebrovascular carbon dioxide reactivity (CVR). This is of upmost …
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Cerebral blood flow in the non-human primate : an in vivo model and drug interventions
… found application in the clinical setting of cerebrovascular diseases such as migraine and dementia. Due to the similarities between humans and non-human primates with respect to their brains, both structurally and behaviourally, numerous studies have been conducted and several non-human …
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Molecular Mechanisms Underlying Alcohol-Induced Cerebral Artery Smooth Muscle BK Channel Inhibition and Eventual Cerebral Vasoconstriction
<p><strong>Introduction and Rationale:</strong> Ethanol (EtOH) at concentrations obtained in circulation during moderate to heavy episodic drinking, such as during binge drinking (30-60 mM) causes cerebral vasoconstriction in many species, including humans. Using rodents as a model to study …