Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Cerebral hemodynamics"”.
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Cerebral Hemodynamics in High-Risk Neonates Probed by Diffuse Optical Spectroscopies
… in these high-risk infants. Assessment of cerebral oxygenation, cerebral blood volume, and the regulation of cerebral blood flow (CBF) during the neonatal period is vital for evaluating brain health. Traditional CBF imaging methods fail, however, for both ethical and logistical reasons. In …
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Cerebral Hemodynamics and Its Oxygenation: Study of Their Baseline and Spontaneous Oscillation
… been especially useful for in vivo monitoring of hemodynamics and oxygen saturation in tissue. For this work, I have developed a large-ranged multidistance probe for NIBS, which allows measurements of cerebral hemodynamics and oxygen saturation. The measurements on the adult forehead were analyzed …
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Cerebral hemodynamics and oxidative metabolism dynamics observed by calibration of functional MRI
Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences and Technology, 1998.
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Effects of increased cerebrospinal fluid adenosine concentration or carbon dioxide tension alterations on cerebral hemodynamics in the dog
Thesis (M.S.)--Michigan State University. Dept.of Physiology, 1975
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Effects of Aerobic Exercise on Cognitive and Cerebrovascular Function in Hypertensive Adults
… of aerobic exercise on 1) arterial stiffness and cerebral hemodynamics and 2) cognitive function in middle-aged adults with controlled-hypertension and without hypertension. Vascular and cognitive measures were assessed pre and post 30-min of aerobic exercise at ≈55% maximal oxygen consumption. …
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Mapping cerebral blood flow with speckle contrast optical spectroscopy
Cerebral blood flow (CBF) is a critical component of cerebral hemodynamics, yet the existing optical neuroimaging modalities to measure CBF do not have sufficient signal-to-noise ratio. Speckle contrast optical spectroscopy (SCOS) has been previously considered as an alternative approach to use …
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Optical Cerebral Blood Flow Monitoring of Mice to Men
This thesis describes cerebral hemodynamic monitoring with the optical techniques of diffuse optical spectroscopy (DOS) and diffuse correlation spectroscopy (DCS). DOS and DCS both employ near-infrared light to investigate tissue physiology millimeters to centimeters below the tissue surface. DOS …
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Exploring The Translational Clinical Value of Cerebrovascular Reactivity Assessments by Diffuse Correlation Spectroscopy
… reactivity (CVR), i.e., the ability of cerebral vasculature to dilate or constrict in response to vasoactive stimuli, is a biomarker of vascular health and CVR quantification is considered an unmet clinical need. However, the value of addressing this unmet need is not clear. This thesis …
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Clinical Applications of Neuromonitoring Following Acute Brain Injury
… clinically to describe the extent to which cerebral hemodynamics and subsequently, patient outcome, have been impacted following acute brain injury (ABI). This Ph.D. thesis examines both prospective and retrospective patient data in both neurocritical and general intensive care patients. …
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MRI based cerebral oxygenation measures in humans : technical development for use across lifespan
MRI based cerebral oxygenation measures could enable brain-centered clinical care and improve understanding of brain energy use throughout human development. We made technical improvements to two MR oxygenation imaging techniques, and explored the concordance between various methods to quantify the …
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Biophysical modeling of hemodynamic-based neuroimaging techniques
… (NIRS) is a promising technique to measure cerebral hemodynamics in a clinical setting due to its potential for continuous monitoring. However, the presence of strong systemic interference in the signal significantly limits our ability to recover the hemodynamic response without averaging …
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Development of Mechanical Optical Clearing Devices for Improved Light Delivery in Optical Diagnostics
… mechanical optical clearing device for measuring cerebral hemodynamics, we demonstrated that mechanical optical clearing devices modify measured cerebral hemodynamic signals in human subjects, improving signal quality.
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Development of High-speed Photoacoustic Imaging technology and Its Applications in Biomedical Research
… functional PAM (fPAM) for high-speed imaging of cerebral hemodynamics in mouse. This fPAM system successfully imaged transient changes in blood oxygenation at cerebral micro-vessels in response to brief somatic stimulations. This fPAM technology is a powerful tool for neurological …
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NNeMo (Neonatal NeuroMonitor) - a hybrid optical system to characterize perfusion and metabolism in the newborn brain
… a further 5-10% develop major disorders such as cerebral palsy. The likelihood of injury increases with a shorter gestational period and/or a lower birthweight. Intraventricular hemorrhaging (IVH) occurs in 20-25% of VLBW infants, characterized by bleeding in the germinal matrix and surrounding …