Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"Cerebral blood volume"”.
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DEVELOPMENT OF IMPROVED ARTERIAL SPIN LABELING METHODS IN HUMANS AND ANIMAL MODELS
… (ASL) is an important tool in evaluating cerebral blood flow (CBF), with applications in clinical imaging for brain tumors and stroke, and as a research tool for brain injury and Alzheimers disease. Multi-TI ASL makes it possible to measure CBF and arterial transit time (ATT). First, …
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Brain segmentation using endogenous contrast mechanism using breath holding fMRI signal for tissue characterization
… changes corresponding to changes in cerebral blood flow (CBF), cerebral blood volume (CBV), oxygen extraction fraction (OEF), and other physiological factors are then estimated and differences between diseased regions and healthy regions are then elucidated.
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Blood-Oxygen-Level-Dependent Parameter Identification using Multimodal Neuroimaging and Particle Filters
The Blood Oxygen Level Dependent (BOLD) signal provides indirect estimates of neural activity. The parameters of this BOLD signal can give information about the pathophysiological state of the brain. Most of the models for the BOLD signal are overparameterized which makes the unique identification …
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Expanding the role of functional mri in rehabilitation research
… magnetic resonance imaging (fMRI) based on blood oxygenation level dependent (BOLD) contrast has become a universal methodology in functional neuroimaging. However, the BOLD signal consists of a mix of physiological parameters and has relatively poor reproducibility. As fMRI becomes a …
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Identifying Patients for Carotid Artery Stenting : Feasibility of Acetazolamide - Challenged Dynamic CT Perfusion
… quantitative measurement, asymmetric index of cerebral blood flow, cerebral blood volume, and mean transit time were determined before and after acetazolamide challenge. Reactivity index was also calculated from asymmetric index of cerebral blood flow before and after acetazolamide challenge. …
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Identifying Patients at Risk for Hyperperfusion after Carotid Stenting Using CT Perfusion with Acetazolamide Challenge
… can occur in patients with preprocedural cerebral hemodynamic impairment who candidate for carotid stent. We investigated whether preprocedural measurement of cerebrovascular reserve (CVR) by using CT perfusion (CTP) with acetazolamide (ACZ) challenge could identify patients at risk for …
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Magnetic particle imaging for intraoperative breast cancer margin assessment and functional brain imaging
… imager is developed and validated for imaging of cerebral blood volume (CBV) changes during functional activation. The goal is improved sensitivity beyond the capabilities of current functional imaging modalities. We present initial results of in vivo rodent fMPI in a small-bore imager, and the …
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The use of conventional and advanced magnetic resonance techniques in the assessment of primary brain tumours
… intervals thereafter. At each visit, tumour volume, maximum rCBV and ADC histogram measures were calculated. This is a unique cohort, as patients were treatment free until malignant transformation was diagnosed, which translates the natural history of these brain tumours. It is unlikely to …
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Cerebral Hemodynamics in High-Risk Neonates Probed by Diffuse Optical Spectroscopies
… in these high-risk infants. Assessment of cerebral oxygenation, cerebral blood volume, and the regulation of cerebral blood flow (CBF) during the neonatal period is vital for evaluating brain health. Traditional CBF imaging methods fail, however, for both ethical and logistical reasons. In …
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Multimodality Imaging of Tumor Vasculature and Metabolism
… tumors and assess the changes in tumor vascular volume and permeability in a mouse model of breast cancer brain metastases. Using a 9.4T system, high resolution anatomic MRI and dynamic susceptibility contrast (DSC) perfusion MRI were acquired at different time points after an intracardiac …
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Towards imaging cerebral microvascular blood flow using MRI
… capillaries and venules, in which the blood flow velocity is slow (≤ 2 cm/s). The hemodynamic signals, blood oxygenation-level dependent response, cerebral blood flow, cerebral blood volume and cerebral metabolic rate of oxygen are the common surrogate markers to detect brain neural …
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The Baroreflex And Neurogenic Control Of Cerebral Autoregulation In Cerebral Blood Flow
Introduction The neurogenic component of cerebral autoregulation (CA) refers to those mechanisms controlling cerebral blood flow under the influence of the nervous system, and which rely on the innervation of the cerebral blood vessels. The neurogenic control of CA is incompletely understood. …
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Mathematical Modelling of Brain Haemodynamics and Pressure-Volume Compensation
… requires an accurate understanding of pressure-volume interactions inside the cranium. This thesis used a hydrodynamic model representing the circulation of cerebral fluids to investigate the relationships between intracranial pressure (ICP) and cerebral blood volume (CBV) changes. The effects …
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Using Multimodal MRI Techniques to Understand the Role of Hippocampus in Schizophrenia
… proton magnetic resonance spectroscopy (1H-MRS), cerebral blood volume (CBV), cerebral blood flow (CBF) and functional MRI at 3T were used to examine the metaplasticity model and probe the role of hippocampus in schizophrenia both with (SZ-on) and without (SZ-off) antipsychotic drug treatment. …
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Model-based reconstruction for correcting magnetic susceptibility-induced artifacts in magnetic resonance imaging
… such as quantitative functional MRI and relative cerebral blood volume estimation. Therefore, for these applications, it is important to obtain R2* estimates which are not dependent on the background magnetic field distribution. However, background SI-MFGs can lead to an overestimation of R2* …
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From fMRI to fUSI: advancing large-scale brain mapping in rodents
… temporally correlated fluctuations in the blood-oxygen-level-dependent (BOLD) signal, forming what are known as resting-state networks (RSNs). In this context, the correlated activity between brain regions, referred to as functional connectivity, is often interpreted as a proxy for …
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Segmentation et extraction de caractéristiques des vaisseaux sanguins cérébraux à l'aide de l'IRM
… is a growing field; it studies the effects of cerebral activity on the behaviour of cerebral blood flow (CBF) and the blood vessels themselves. With the help of magnetic resonance imaging (MRI), it is possible to obtain images such as susceptibility weighted imaging (SWI) to see the veins or …