Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 80 for “"Cerebral artery"”.
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Posterior cerebral artery (PCA) infarcts and dreaming : a neuropsychological study
… infarction in the territory of the posterior cerebral artery were recruited in this study. Case histories and neuroradiological data were used to compare the lesion sites of non-dreamers with dreamers. It was confirmed that complete loss of dreaming could result from lesions in medial …
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Modulation of Cerebral Artery Smooth Muscle BK Channel Function by Neurosteroids
… probability is linked to increased dilation of cerebral arterial smooth muscle. The tissue specificity and functional effects of the β1 subunit offer a unique opportunity for the identification of pharmacological activators to be developed with few off-target effects. While many steroids have …
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Protein Trafficking of BK Channel β1 Subunits in Cerebral Artery Myocytes
… and mental dysfunction. During hypertension, cerebral arteries have high myogenic tone and are less responsive to vasodilators, including nitric oxide (NO). The regulation of arterial contractility by BK channels is altered during hypertension, although mechanisms involved are also unclear. …
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Evaluating Longitudinal Motor Recovery in Non-Human Primates after Middle Cerebral Artery Occlusion
… sensorimotor recovery of NHPs following Middle Cerebral Artery Occlusion (MCAO) by assessing performance with both NHPSS and Kinarm. Additionally, magnetic resonance imaging (MRI) will be used to confirm stroke morphology, and volume, and examine its relationship with functional recovery. …
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Cholesterol Modulation of BK Currents and Cerebral Artery Diameter Via Channel-Forming Alpha-Subunit
… with the BK channel alpha subunit results in cerebral artery diameter physiological responses. Specifically, we addressed the physiological and pharmacological consequences of cholesterol-BK channels protein interaction via Y450. While results demonstrate a lack of change in mouse middle …
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Molecular Mechanisms Underlying Alcohol-Induced Cerebral Artery Smooth Muscle BK Channel Inhibition and Eventual Cerebral Vasoconstriction
… such as during binge drinking (30-60 mM) causes cerebral vasoconstriction in many species, including humans. Using rodents as a model to study ethanolinduced cerebral artery constriction, our laboratory demonstrated that ethanol-induced cerebral artery constriction is due to drug-induced …
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Doppler ultrasound technique used to determine the blood flow viscosity in the middle cerebral artery of a canine animal model
The cerebral blood flow velocity in the middle cerebral artery of an canine animal model was measured using the Doppler Ultrasound technique. A transducer was designed with a 20 MHz piezoelectric crystal and used for the application. An in vitro calibration system was designed and machined for the …
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Comparison of transplantation modality of human mesenchymal stem cells expressing neurogenin1 in rat middle cerebral artery occlusion model: intra-arterial vs. intra-cerebral
… progression. In our previous study, intra-cerebral transplantation of neurogenin1-expressing MSCs (MSCs/Ngn1) in the animal stroke model dramatically improved neurologic deficits compared with the parental MSCs. However, intra-cerebral transplantation is an invasive method and inappropriate …
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Unraveling the Role of EphA4 in Immune-Mediated Arteriogenesis After Ischemic Stroke
… events often caused by occlusion of the middle cerebral artery (MCA). Pre-existing leptomeningeal collateral (LMC) vessels connect MCA branches to anterior or posterior arteries, situated along the brain's cortical surface or meninges, under healthy conditions these vessels remain dormant due to …
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Investigating white matter alterations and secondary neurodegeneration with MRI imaging and pathology in a mouse model of ischaemic stroke
… the corpus callosum and thalamus after a middle cerebral artery stroke may contribute to cognitive decline. The aim of the current study was to examine remote grey and white matter alterations in anatomically connected brain regions following experimental cortical ischaemic stroke, with a …
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CHOLESTEROL INDUCED GENE EXPRESSION CHANGES IN THE BRAIN AND CEREBRAL VESSELS
… on gene expression changes in the brain and cerebral vessels, which may contribute to these disorders. Present findings showed that cholesterol exerted different acute and chronic effects on gene expression in both regions. Acute intracortical administration of oxysterols at low concentration …
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A dissection and angiographic study of anatomical variations in the anterior communicating artery complex in a South African sample
The anterior communicating artery complex (ACAC) consists of the A1 and A2 segments of the anterior cerebral artery (ACA) and the anterior communicating artery (ACoA). The ACAC is said to be the most frequent site of aneurysms and anterior cerebral circulation variations. Clear correlation between …
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The influence of acute, chronic and lifelong hypoxia on the functional and structural integrity of the neurovascular unit
… to measure extracranial (internal carotid artery blood flow [ICA<sub>Q</sub>] and vertebral artery blood flow [VA<sub>Q</sub>]) and intracranial (middle cerebral artery blood velocity [MCA<sub>V</sub>] and posterior cerebral artery [PCA<sub>V</sub>]) haemodynamics. Global cerebral blood …
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Action of halothane on large-conductance, calcium-activated potassium channels in rat cerebrovascular smooth muscle cells
Halothane anesthesia is associated with increased cerebral blood flow and dilatation of cerebral vessels. The mechanisms which underlie this drug action are presently unclear. Cerebrovascular tone is probably regulated in part by the opening of large conductance, Ca²⁺-activated potassium channels …
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Occluson Pattern in Circle of Willis: Prognostic Marker for Endovascular Treatment in Acute Carotid Terminus Occlusion
… of Willis and the occlusion pattern of each cerebral artery and divided patients into middle cerebral artery (MCA) only group and MCA plus group by CT angiography. Patients in MCA only group had only MCA occlusion whereas those in MCA plus group had other major intracranial artery occlusion …
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Clinical Significance of Pattern of Memory Deficits in Amnestic Mild Cognitive Impairment
… of Willis and the occlusion pattern of each cerebral artery and divided patients into middle cerebral artery (MCA) only group and MCA plus group by CT angiography. Patients in MCA only group had only MCA occlusion whereas those in MCA plus group had other major intracranial artery occlusion …
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Imaging biological water permeability barriers using CARS microscopy
… CARS examination of water permeability in the cerebral artery and blood brain barrier. The vessels of mice deficient in the water channel protein aquaporin 1 (AQP1) were examined to evaluate the role of AQP1 in vascular water permeability. A layered hydrogel imaging phantom was constructed from …
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Role of Cofilin, an Actin Cytoskeletal Protein, in Ischemic Conditions: Potential Therapeutic Target for Ischemic Stroke
Cerebral ischemia or stroke is a condition associated with decreased blood supply to brain leading to death of neurons. It is associated with a diverse cascade of responses involving both degenerative and regenerative mechanisms. Actin cytoskeleton changes play a key role in mediating these …
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Effects of Cerebral Blood Flow and Temperature on Executive Function During Moderate Hyperthermia
… heat stress may be affected by changes in cerebral blood flow (CBF) as opposed to thermal perception changes. An end-tidal forcing system was used to maintain eucapnia and baseline CBF in the isocapnic trial during the hypocapnia-induced CBF reduction. Repeated measures analysis of variance …
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An electronically steered, wearable transcranial doppler ultrasound system
… Doppler (TCD) ultrasound system to measure cerebral blood flow velocity (CBFV) at the middle cerebral artery (MCA). TCD sonography has been clinically indicated in a variety of neurovascular diagnostic applications. Acceptance of conventional TCD methods, however, has been primarily impeded …
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