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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 33 for “"Cephalosporin"”.
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Metal complexes of penicillin and cephalosporin antibiotics
… between metal-ions and the penicillin and cephalosporin antibiotics have been studied in an attempt to determine both the site and mechanism of this interaction. The solution conformation of the Cu(II) and Mn(II) complexes were determined using an n.m.r, line broadening, technique. The …
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Synthesis of D-alanyl-D-alanine dipeptide isosteres and cephalosporin prodrugs
… Several reports have been made which use a cephalosporin prodrug with a dual mode of action. Antibiotics are coupled to cephalosporin intermediates and produce a compound which is capable of acting as an antibiotic on its own as well as delivering the coupled antibiotic into the periplasm by …
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ENABLING RAPID PHENOTYPIC DETECTION OF CEPHALOSPORIN RESISTANCE BEYOND THE CENTRAL LABORATORY
… antibiotics, including a drug class known as cephalosporins used to treat many hospital and community-acquired infections. This major public health threat has been acknowledged for decades by the Centers for Disease Control (CDC) as a major concern; yet, the detection of superbugs has not been …
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The Impact of Ceftiofur Removal on Recovery of Salmonella enterica and Escherichia coli Resistant to Third Generation Cephalosporins
… would have on the reduction of third generation cephalosporin resistance mediated by the ¿¿-lactamase gene, blaCMY-2, among Salmonella enterica and Escherichia coli organisms.</p><p>The purpose of our study was to establish a baseline prevalence of third generation cephalosporin resistance among …
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Identification and characterisation of cephalosporins and carbapenem-resistant Klebsiella pneumoniae isolates from Misrata, Libya
… Gram-negative bacilli showing resistance to cephalosporins and carbapenems respectively, have been reported from several countries globally and recently among Libyan combatants who have been transferred to European countries for advanced medical care. However, there is a lack of data about …
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Antibiotic Resistance: Multi-Drug Profiles and Genetic Determinants.
… Kirby Bauer disk assays were performed for 7 cephalosporin and 4 non-cephalosporin antibiotics.</p> <p>In summary, 2 observations implicate more complex resistance determinants than the 2 known forms of the BRO β-lactamase. First, there was overlap in the ranges of inhibition zones. Second, …
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A Clinical Characteristics of Adverse Drug Reaction in Pediatrics
… of penicillin type (18 patients, 18%), Cephalosporin (7 patients, 7%), Macrolides (3 patients, 3%), NSAID (13 patients, 13%), Acetaminophen (8 patients, 8%), Phenytoin (12 patients, 12%), Anti-cancer medicine (4 patients, 4%), Sedative (1 patient, 1%) and Antiflammatory (1 patient, 1%). …
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The Effect of Thermophilic Anaerobic Digestion on Ceftiofur and Antibiotic Resistant Gene Concentrations in Dairy Manure
… reactors and the type of antibiotic studied. Cephalosporin drugs are the most common antibiotic class used to treat mastitis in dairy cows and can retain most of their bioactivity after excretion. Ceftiofur is a commonly used cephalosporin drug but no previous study investigating the effect of …
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A spontán bakteriális peritonitis
… indítandó empirikus antibiotikumterápia (3.gen. Cephalosporin). Profilaktikusan norfloxacin adható a megfelelő esetekben. A gyors diagnózissal, és megfelelő kezeléssel a mortalitása visszaszorítható akár 20-30%-ra is (az 1960-as évekbeli közel 90%-ról).
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Treatment of Group A Beta-Hemolytic Streptococcal tonsillopharyngitis: Cephalosporins Versus Penicillins
… could be used as a first-line treatment option. Cephalosporins emerged as a possible alternative.</p> <p>The purpose of this project was to analyze current evidence and compare the bacteriologic efficacy of cephalosporins and penicillins for treatment of GABHS tonsillopharyngitis. A substantial …
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Klebsiella pneumoniae bloodstream infections in hospitalised children at Red Cross War Memorial Children's Hospital : 2006 - 2011
… of ESBL-KP bloodstream infection included cephalosporin exposure in the preceding 12 months prior to the KPBSI p=<0.0001: aRR 1.25 (95% CI: 1.15-1.36); and those who had intravenous infusions for more than 3 days prior to the KPBSI, p=0.004: aRR 1.18 (95% CI: 1.05-1.31).
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Antimicrobial Nanoparticles: A Green and Novel Approach for Enhancing Bactericidal Efficacy of Commercial Antibiotics
… the combined reducing and capping ability of a cephalosporin antibiotic, ceftazidime. No signs of aggregation or leaching of ceftazidime from GNP surface was observed upon its storage. Antibacterial testing showed dosedependent broad spectrum activity of Cef-GNPs against both Gram-positive (S. …
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Understanding the Solid State, Solubility and Dissolution Behavior of Cefuroxime Axetil Diastereomers in Interactive Mixture Formulations
… the solid-state and solution behavior of a cephalosporin antibiotic prodrug, cefuroxime axetil (CFA). CFA is present in commercial products as a mixture of diastereomers, which commonly form eutectic mixtures. A phase diagram was constructed utilizing differential scanning calorimetry. It …
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Microbiological profile of surgical site infections in orthopedic surgery at the university teaching hospital; Lusaka, Zambia.
… and third and fourth-generation cephalosporin. The percentages of the sensitive P. aeruginosa isolates against most antibiotics were relatively low in this study. There was no significant association between the various factors and SSI, each with a p-value greater than 0.05. …
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Microbiological profile of surgical site infections in orthopedic surgery at the university teaching hospital; Lusaka, Zambia.
… and third and fourth-generation cephalosporin. The percentages of the sensitive P. aeruginosa isolates against most antibiotics were relatively low in this study. There was no significant association between the various factors and SSI, each with a p-value greater than 0.05. …
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ΔΙΕΙΣΔΥΣΗ ΤΗΣ ΚΕΦΤΡΙΑΞΟΝΗΣ ΣΤΟΝ ΠΡΟΣΤΑΤΙΚΟ ΙΣΤΟ
CEFTRIAXONE, A NEW SEMISYNTHETIC PARENTERAL CEPHALOSPORIN WITH HIGH ACTIVITY AGAINST BOTH GRAM POSITIVE AND NEGATIVE ORGANISMS WAS FOUND TO HAVE UNIQUE PHARMACOKINETIC PROPERTIES WHICH ALLOWS ONCE A DAY ADMINISTRATION. CLINICAL TRIALSSHOWED ITS EXCELLENT CLINICAL EFFICACY AND SAFETY AND ALSO ITS …
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ΚΙΝΗΤΙΚΗ ΤΗΣ ΚΕΦΑΔΡΟΞΙΛΗΣ ΣΤΟ ΜΗΤΡΙΚΟ ΓΑΛΑ. ΕΠΙΔΡΑΣΗ ΣΤΗ ΜΙΚΡΟΒΙΑΚΗ ΧΛΩΡΙΔΑ ΤΟΥΣΤΟΜΑΤΟΦΑΡΥΓΓΑ ΚΑΙ ΤΟΥ ΕΝΤΕΡΟΥ ΣΤΟ ΝΕΟΓΕΝΝΗΤΟ ΠΟΥ ΘΗΛΑΖΕΙ
CEFADROXIL IS AN ORAL CEPHALOSPORIN WITH HIGHER LIPID SOLUBILITY THAN OTHER MEMBERS OF THIS GROUP OF ANTIBIOTICS. IN A PREVIOUS STUDY IT HAS BEEN SHOWN THAT CEFADROXIL PRODUCES HIGHER ANTIBIOTIC CONCENTRATIONS IN HUMAN MILK. IN ORDER TO INVESTIGATE WHETHER THESE CONCENTRATIONS HAD ANY EFFECT ON …
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Optimization of a Method for Testing Ballast Water for Enterococci and an Investigation on the Occurrence of Antibiotic Resistance in Vibrio cholerae
… second-, third- and fourth- generation cephalosporins were tested by disk diffusion. Genotypic analysis of the resistance determinants was performed by PCR to detect ESBL (blaCTX, blaTEM, blaSHV), carbapenemases (blaIMP, blaSPM, blaVIM, blaBIC, blaNDM, blaKPC, blaAIM, blaSIM, blaDIM, and …
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Development and validaton of an indicator to compare antibiotic usage in secondary care in England
… of third generation to first/second generation cephalosporin use, and five percent as the limit for parenteral quinolone DOD of total quinolone DOD usage. It was possible to demonstrate a correlation between the IMD 2000 and primary care antibiotic prescribing rates but not between primary and …
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