Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"Central nervous system disorders"”.
-
Drug discovery at class A and class B GPCRs
… as cancer, diabetes mellitus, inflammation or central nervous system disorders. This makes GPCRs the focus of drug discovery with roughly 34% of all FDA (Food and drug administration) approved drugs targeting them. This thesis presents the drug discovery at adenosine receptors, class A GPCRs, …
-
Forever gluten-free: exploring the psychosocial impact of living with coeliac disease
… gynaecological problems in women, peripheral and central nervous system disorders and other autoimmune diseases. In Europe it is estimated that the condition may affect between 1 in 200 to 1 in 500 people. CD is incurable but symptoms are managed by a gluten-free diet (GFD) for life. Most research …
-
Behavioral and Neurochemical Characterization of the Effects of the Novel Adenosine Antogonist MSX-4
… Moreover, previous studies have shown that systemic administration of adenosine A<sub>2A</sub> antagonists reverses the behavioral effects of DA-R D2 antagonists in rats responding on the concurrent choice task. MSX-3, a selective adenosine A<sub>2A</sub> antagonist, is a prodrug of MSX-2 …
-
Targeting Airway Microbiome Dysbiosis for Preventing Pediatric Subglottic Stenosis
… such as congenital heart disease and central nervous system disorders. In SGS, fibroblasts deposit aberrant extracellular matrix resulting in a fibrous scar and airway narrowing between the vocal folds and the inferior border of the cricoid cartilage. Most cases require repeated …