Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 10 of 10 for “"Central Sensitisation"”.
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Does distress predict central sensitisation in people living with HIV?
… mental health in many people with HIV (PWH). Central sensitisation (CS) is a hallmark of most persistent pain conditions. Pain and psychosocial distress (PSD) appear to have a bidirectional relationship. Therefore, it is plausible that PSD contributes to pain by increasing central …
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Improving clinical outcomes in rheumatoid arthritis: a patient centred approach
… not directly addressed. The research showed central sensitisation causes persistent pain in many RA patients; it may require different management approaches. The research also characterised patients with the fibromyalgic rheumatoid clinical phenotypes; their higher disease activity scores may …
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The Psychology of Anxiety & Pain in Fibromyalgia
… pain comes from psychophysical research of central sensitisation, a phenomenon of abnormally amplified pain following disruptions in the central nervous system. Anxiety has been long theorised to mediate this centralised pain, but its contribution is yet to be characterised. This thesis …
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Role of Central Sensitivity Syndromes in women with pelvic organ prolapse
Title- Role of Central Sensitivity Syndromes in Women with Pelvic Organ Prolapse. Author- Monika Vij Pelvic Organ Prolapse (POP) is a dysfunction of pelvic floor support and have an ad-verse effect on the quality of life (QOL). The predominant symptom is the feeling of a vaginal bulge. However, a …
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An Evaluation of passive recumbent quantitative fluoroscopy to measure mid-lumber intervertebral motion in patients with chronic non-specific low back pain and healthy volunteers.
… It is likely that other factors such as loading, central sensitisation and motor control may also be responsible for back pain that is considered mechanical. QF is easily adapted to clinical practice and is recommended to replace functional radiography, but further work is needed to determine …
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Cervico-mandibular muscle activity in females with chronic cervical pain a descriptive, cross-sectional, correctional study
… and maintenance of chronic pain, through central sensitisation. There appears to be a neurophysiological, biomechanical and psychological link between the cervical area and the temporomandibular area. Although numerous studies have implied that individuals with temporomandibular disorders …
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Impact of environmental and genetic factors on pain sensitivity and chronic pain development
… alterations in skin innervation, cell bodies or central termination pattern of primary afferents. This thesis highlights a potentially novel mechanism contributing to dynamic allodynia, with the development of Meissner’s corpuscles at the incision site amplifying input during central …
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Neurosteroids: endogenous analgesics?
Peripheral sensitisation and central sensitisation are implicated in the development of neuropathic pain with neuroplasticity occurring at multiple levels of the pain pathway. Hypersensitivity of the spinothalamic tract has been described in neuropathic animal models of diabetes. Spinal dorsal horn …
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Codeine, heightened pain sensitivity and medication overuse headache: a neuroimmune hypothesis and novel treatment strategy.
… derives from a cumulative interaction between central sensitisation and glial priming, due to repeated activation of nociceptive pathways by recurrent headaches, and pain facilitation due to glial activation and subsequent neuroinflammation. The first part of this thesis examines the efficacy …
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Plasticity in mice nociceptive spinal circuits -role of cell adhesion molecules.
… that the current view on the locus of the central sensitization mechanisms needs to be reconsidered. In the second part of the thesis, the role of the cell adhesion molecule L1 in the pain system was studied in mutated mice. Interestingly, these animals were found to be almost analgesic. …