Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 48 for “"Central Composite Design"”.
-
A central composite design to investigate antibody fragment production by Pichia pastoris
… rate, protein expression), by a 3-factor-3-level central composite factorial design. This experimental design involved running shake flask culture at 15 different experimental conditions with duplicates. Optical density (OD600), dry cell weight (DCW), and BCA Protein Assays were done on each …
-
Recommendations for Design Parameters for Central Composite Designs with Restricted Randomization
In response surface methodology, the central composite design is the most popular choice for fitting a second order model. The choice of the distance for the axial runs, alpha, in a central composite design is very crucial to the performance of the design. In the literature, there are plenty of …
-
Improving Response Characteristics of Split Ring Resonators Using Experimental Designs
… this thesis is to investigate the application of design of experiments approaches in the analysis of split ring resonators, and to compare two different approaches. The design parameters of the meta-material device are examined to study all the main effects, the two factor interactions, and the …
-
Decision-Based Design of New Products: Electrothermal Swing Adsorption (Esa) System
… A response surface methodology using Central Composite Design is then used to optimize the operation of the ESA system. The results of the experiments also provide inputs to the multiattribute evaluation and design optimization. Finally, an assessment of ESA technology in terms of its …
-
Experimental Investigation of the Effect of Composition on the Performance and Characteristics of PEM Fuel Cell Catalyst Layers
… the role of catalyst layer composition using a Central Composite Design (CCD) experiment with two factors which are Nafion content and carbon loading while the platinum catalyst surface area is held constant. For each catalyst layer composition, polarization curves are measured to evaluate cell …
-
An experimentally designed melt rheological characterization of starblock polymers
… polymers was investigated using the experimental design technique of response surface methodology. A rotatable central composite design (ccd) was employed with linear 2⁵ factorial structure and with axial points to fit the pure quadratic terms. Regression analysis of rheological data from …
-
Investigation of operating parameters in a vertical stirred mill
… a statistical analysis. The experiments was designed using a face centred central composite design (FCCD) and the results was statistically analysed using a design of experiments (DOE) software.
-
Short-term traffic forecasting for a smart satellite communications system
… Each algorithm was tuned using a two-stage design of experiments process consisting of a fractional screening design to identify impactful hyper-parameters and a central composite design to find optimal model settings. During a holdout period, the mean absolute percentage error using a …
-
Method of reliability-based calibration of seismic structural design parameters
Structural design under seismic load requires proper consideration of uncertainties associated with loads and resistance as well as the limited ability of analytical models to describe the response of a structure. To account for these uncertainties, the design parameters in current seismic codes …
-
Aggregate gradation impacts on fresh properties of 3D concrete printing mixtures
… mixes and the lack of standardized mixture design frameworks. Existing literature on 3DPC identifies qualities of printable mixtures, such as a range in fluidity/rheology where the mixture’s pumpability, extrudability, and buildability requirements are met. However, no comprehensive …
-
Data Driven Surrogate Based Optimization in the Problem Solving Environment WBCSim
Large scale, multidisciplinary, engineering designs are always difficult due to the complexity and dimensionality of these problems. Direct coupling between the analysis codes and the optimization routines can be prohibitively time consuming. One way of tackling this problem is by constructing …
-
Optimization of extraction parameters of selected Malaysian plants towards antiurolithiatic activities (IN-VITRO)
… time that was screened using two-level factorial design and optimized by response surface methodology and central composite design. The results showed that optimum extraction condition for A. occidentale extract (0.4% ethanol, 31.5°C, 30 minutes) on both antiurolithiatic activities were exhibited …
-
Harvesting of microalgae botryococcus sp. Through phycoremediation of bathroom greywater
… through Response Surface Methodology (RSM) design expert software. Botryococcus sp. was inoculated in bathroom greywater with 4.5 x 106 cell/mL for phycoremediation process. Microalgae Botryococcus sp. grown in bathroom greywater from House A, House B and House C and tested for reduction of …
-
Development and optimization of zeolite synthesis route from natural koalin for adsorption of dyes
… process. Hence, this study employed 2k factorial design of experiment to study the relationship of metakaolinization temperature of 600 – 800 oC with calcination time of 1 – 5 hours. And that of crystallization time of 9 – 16 hours with aging treatment time of 12 – 36 hours. Central Composite …
-
Evaluation of the effect of growth conditions on lipid production by Papiliotrema laurentii UFV-1 in culture media containing xylose
… from soil. We performed the centered face central composite design, with 25 combinations between the factors studied and three replicates at the central point, to evaluate their effects on the response variable lipid content. The highest lipid content (41.26%) was obtained in the following …
-
Effects of acid hydrolysis conditions on cellulose nanocrystal yield and properties: A response surface methodology study
… for maximum CNC yield. Two experimental designs were tested and compared: the central composite design (CCD) and the Box–Behnken design (BBD). The three factors for the experimental design were acid concentration, hydrolysis temperature, and hydrolysis time. The responses quantified were …
-
Optimization of spodumene flotation with fatty acid collectors
… acid impurities in commercial TOFA collectors. A Central Composite Design (CCD) of experiment investigated conditioning parameters and pH behaviour, which later guided collector adsorption studies using Time of Flight-Secondary Ion Mass Spectroscopy (ToF-SIMS) and X-ray Photoelectron Spectroscopy …
-
Catalytic Conversion of Glycerol to Glycerol Carbonate Utilizing CO₂ and Dimethyl Carbonate
… glycerol carbonate yield, various catalysts were designed for the glycerol and DMC reaction. Lithium oxide combined with synthesized activated carbon, using incipient wetness impregnation method, performed best, achieving an 87.9±2.4% yield due to its high basicity and surface area. The activated …
-
Solubility Enhancement and Precipitation Inhibition of Poorly Water Soluble Compounds Utilizing Hot Melt Extrusion Technology
… also demonstrated a higher solubility. </p> <p>A central composite design (CCD) was applied to optimize the processing parameters for KTZ-SOL solid dispersions and the final formulation containing 29.8% drug was extruded at a temperature of 140°C and screw speed of 31 rpm. The robustness of the …
Page 1 of 3