Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Cellular morphologies"”.
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Regulatory Mechanisms of Mitotic Catastrophe Induced by Doxorubicin
… We used human hepatoma (Huh-7) and human hepatocellular carcinoma cell lines (SNU-354, -398, -449, and -475) to distinguish the mode of low doses (LD) of doxorubicin-induced cell death from that of apoptosis induced by high doses (HD) of the same drug, morphologically and biochemically, and …
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Nutlin-3 sensitizes cancer cells to bortezomib via induction of paraptosis-associated cell death
… 80-90% of proteins, and is central to regulating cellular function and keeping protein homeostasis. Since proteasome inhibition can lead to the accumulation of the misfolded proteins and subsequent proteotoxicity in tumor cells, the proteasome is considered a target for cancer therapies. …
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Biocompatibility Investigations of Surgical Implant Alloys.
… responses (inhibited growth rates and altered cellular morphologies) at concentrations as low as 3.0 ppm (representing in ppm 2.0 Fe, 0.6 Cr, and 0.42 Ni). Cell cultures exposed to Co-Cr-Mo solutions demonstrated toxic responses at 1.5 ppm (representing in ppm 1.0 Co, 0.45 Cr, and 0.09 Mo). …
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Tissue-specific adaptations of cell types
… and organisms in Nature. Across these, common cellular morphologies and functions have been identified. High-throughput, multifactorial profiling of cells has grown exponentially in recent years with the advent of single-cell RNA-sequencing (scRNA-seq), increasingly unravelling cell diversity. …
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The Role of Small Peptides in Cancer Physiology and Chemotherapy
… revealing reduced cell numbers, aberrant cell morphologies, and cell destruction where drug treatment had been demonstrated to alter membrane integrity and/or cell proliferation was observed, i.e. beta-alanyl-melphalan treatment of mouse liver cells, cellular morphologies were demonstrated to …
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Rethinking Plant-Based Materials Production: Selective Growth of Tunable Materials Using Cell Culture Techniques
… (1) establishing knowledge to effectively direct cellular development, (2) devising and demonstrating mechanisms to direct material form, and (3) relating cellular-level properties to emergent material characteristics to allow tunable and predictable material outcomes. First, using newly proposed …
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Investigating the effect of a Mycobacterium tuberculosis inhA promoter mutation in cell envelope composition and morphology
… (SEM) was implemented to visualise extracellular surface features and determine cell length, while transmission electron microscopy (TEM) was used to examine ultrastructural cell wall layer distances. To further understand the architecture and organisation of M.tb cell wall we assessed …
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Mechanical Design of Selected Natural Ceramic Cellular Solids
… structure and mechanical properties of natural cellular solids such as wood and trabecular bone have been extensively studied in the past, the structural design and underlying deformation mechanisms of natural cellular solids with very high mineral contents (> 90 wt%), which we term as natural …