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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 66 for “"Cellular Membrane"”.

  1. Mechanism Governing the Cellular Susceptibility to Secretory Phospholipase A2

    Jensen, Lauren Blackburn2004

    … attack by sPLA2. Recent studies have focused on membrane properties necessary to induce susceptibility in both artificial and biological membranes. Hydrolysis of phospholipids by sPLA2 requires at least two preliminary steps: first, adsorption of the enzyme to the cellular membrane, and second, …

    byu Repository record

  2. Proteomic analysis of Pseudomonas putida F1 during growth on toluene-phenol mixtures

    Kim, Kee-Hong, author, Reardon, Kenneth F., advisor, Murphy, V. G., committee member, Linden, James, committee member, Belisle, John T., committee member, Schweizer, Herbert P., committee memberColorado State University. Libraries2002

    … changes in the phospholipid fatty acids of the cellular membrane. The phospholipid fatty acid composition was found to dramatically change depending on the growth substrate(s). These membrane compositional changes during the biodegradation of the toluene-phenol mixture were used to form the …

    colostate Repository record

  3. Cofactors in Coronavirus Entry

    Shulla, Ana2016

    … important barriers the virus has to cross is the cellular membrane. Enveloped viruses accomplish this task by viral glycoprotein-mediated binding to host cells and fusion of virus and host cell membranes. For the coronaviruses, viral spike (S) proteins execute these cell entry functions. In my …

    loyola-thes Repository record

  4. BIOCHEMICAL CHARACTERIZATION OF ETHANOL MODIFIED PHOSPHOLIPIDS IN SACCHAROMYCES CEREVISIAE

    SHEN TONG2014

    … (PETH) IS REGARDED AS AN ABNORMAL LIPID IN CELLULAR MEMBRANE, UNIQUELY FORMED FROM PHOSPHATIDYLCHOLINE VIA PHOSPHOLIPASE D-CATALYZED TRANSPHOSPHATIDYLATION IN THE PRESENCE OF ETHANOL. IT HAS A DISTINCTLY DIFFERENT CHEMICAL STRUCTURE COMPARED WITH OTHER PHOSPHOLIPIDS AND MAY PERTURB THE …

    nus Repository record

  5. The Role of Membrane-Bound Receptors in the Rapid Estrogenic Enhancements of Learning and Memory Within the Hippocampus

    Kuun, TalyaUniversity of Guelph2021

    … rapid estrogenic effects are mediated solely by membrane-bound estrogen receptors is currently unknown. This study sought to determine the role of membrane estrogen receptors in the rapid effects of 17-β estradiol within the hippocampus. By conjugating 17-β estradiol to a large bovine serum …

    guelph Repository record

  6. Aquaporin 3 Water Channel Protein Gene Expression in Squalis Acanthias Dogfish Shark

    Murray, Debra Lee2014

    Aquaporins are a family of membrane proteins that provide channels for the rapid movement of water molecules and some small solutes across the cellular membrane. Since the discovery of the first water channel protein, hundreds of homologous proteins have been found in all forms of life and much has …

    gsu Repository record

  7. Tetraspanin CD9: Contributions to Cancer Cell and Vascular Cell Phenotypes from the Sixth Man

    Herr, Michael James, II2016

    … are cell surface proteins that organize the cell membrane. Cellular membrane organization is a prerequisite for cellular signaling to occur. Deregulation of cellular signaling often precedes the formation of cancer or vascular disease phenotypes. This insinuates the necessity to understand how …

    tenn-hsc Repository record

  8. The missing dimension of cell membrane organization. Study on cubic membrane structure and function

    ZAKARIA ALI MOH. ALMSHERQI2010

    Membranes are of fundamental importance for biological systems. They provide for cellular compartmentalization and control of the internal cell environment. The biophysical properties of the membrane lipids and proteins play a key role in determining the membrane morphology and geometry. Far from …

    nus Repository record

  9. Membrane fragmentation by a 20-29 fragment of human islet amyloid polypeptide and rat amyloid polypeptide

    Samisetti, Shyamprasad2007

    … aggregates that kill β-cells by disrupting the cellular membrane. In this study we report membrane fragmentation by hIAPP20-29 and the rat version, rIAPP20-29, using solid-state NMR experiments on nanotube arrays of anodic aluminum oxide containing aligned phospholipid membranes.</p> <p>31P NMR …

    emich Repository record

  10. One-Step Synthesis of Kanamycin Functionalized Gold Nanoparticles With Potent Antibacterial Activity Against Resistant Bacterial Strains

    Waghwani, Hitesh Kumar

    … their bactericidal action through disrupting the cellular membrane resulting in leakage of cytoplasmic content and death of bacterial cells. Results of this study provide a novel method in the development of antibiotic capped GNPs as potent next-generation antibacterial agents.</p>

    wku-diss Repository record

  11. Role of Bcl-2 proteins in neutrophil activation and delayed apoptosis in crystal-induced arthritis

    Higo, Tobi T.University of British Columbia2008

    … by the binding of the crystals to the neutrophil cellular membrane, which leads to respiratory burst activity, engulfment of the crystals and release of proteolytic enzymes. Furthermore, we have found that crystals delay the normal “cell death program” or apoptosis, thus allowing for the …

    ubc Repository record

  12. Biomolecular interactions and cellular effects of steroidal and metallosupramolecular metallodrugs

    Sanchez-Cano, CarlosUniversity of Birmingham2009

    … and the ability to reach their possible intracellular targets of certain steroidal metallodrugs and metallosupramolecular cylinders. Chapter 1 surveys the background to the project, surveying different DNA-binding modes, explaining their importance in the anticancer properties of metallodrugs …

    birmingham Repository record

  13. Antimicrobial Nanoparticles: A Green and Novel Approach for Enhancing Bactericidal Efficacy of Commercial Antibiotics

    Shah, Monic

    … P. aeruginosa and E. durans by disrupting the cellular membrane resulting in leakage of cytoplasmic content and death of bacterial cell. Our investigation and results provides an additional step in the development of antibiotic capped GNP as potent next generation antibacterial agents.</p>

    wku-diss Repository record

  14. Self-assembly of aurfactant-like amphiphilic peptides made of natural amino acids

    Yang, Steve J., 1976-Massachusetts Institute of Technology2004

    … One such important problem is the study of membrane proteins, most of which are not amenable to biochemical or structural studies due to their inherent insolubility and instability outside of the natural cellular membrane. Here we describe the development and behavior of a new class of …

    mit Repository record

  15. Applying secondary ion mass spectrometry to cellular and model membranes to image component distribution and quantify composition

    Wilson, RobertUniversity of Illinois at Urbana-Champaign2013

    … (SIMS) returns chemically specific data on membrane component distribution and composition. Of particular interest is a membrane protein’s lipid environment, which may play a role in the protein’s function. Herein, this thesis describes the synthesis of fluorine-functionalized colloidal gold …

    uiuc Repository record

  16. Detection and enrichment of cytochrome P450s using bespoke affinity chromatography and proteomic techniques. Development of chemical immobilisation and novel affinity chromatography methods, with subsequent proteomic analysis, for the characterisation of cytochrome P450s important in cancer research.

    Bateson, HannahUniversity of Bradford2013

    Introduction: Cellular membrane proteins, such as the cytochrome P450 enzyme superfamily (P450), have important roles in the physiology of the cell. P450s are important in metabolising endogenous molecules, as well as metabolising xenobiotic substances for detoxification and excretion. P450s are …

    bradford Repository record

  17. COMPARISON OF E. COLI AND Y. PESTIS LPS TLR4 TIME COURSE ON P388D1 MACROPHAGES USING FLUORESCENT CONJUGATED ANTIBODIES

    Kleven, Julia

    The innate immune system enables cellular response to infectious agents, and protein interactions are essential for this response. However, the protein interactions involved in cellular response to pathogens are not completely understood. Clarifying the manner in which proteins bind and respond to …

    unm Repository record

  18. Cationic Polymers and Polymeric Micelles as Plasmid DNA and CRISPR-Cas9 Ribonucleoprotein Delivery Vehicles

    Tan, Zhe2019

    … polymers with liver-targeting ability and cellular membrane-penetration property have been developed and studied for their gene delivery efficiency and cytotoxicity.

    umn Repository record

  19. Antiviral activity of 3D8 single chain Fv against RNA virus infection

    전, 혜령2012

    … activity by electrostatic interaction with cellular membrane and it localizes in cytosol resulting in cell death by cellular rRNA degradation. These result mean that 3D8 scFv would also have potential activity as an intracellular antiviral antibody. Since 3D8 scFv has RNase activity, 3D8 …

    ajou Repository record

  20. Lipid and Protein Sorting by, and Generation of, Membrane Curvature in Model Systems

    Heinrich, Michael C2011

    … of liquid-liquid phase separation in lipid membranes to the formation and stability of “lipid rafts” in cellular plasma membranes has prompted extensive investigation of the physical chemistry underlying these phenomena. Furthermore, the concept of lipid rafts – 10-200 nm regions of cellular …

    penn Repository record

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