Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Cellular Maintenance"”.
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Energetics of substrate unfolding by ClpA
… for proteolysis. ClpA's in vivo contribution to cellular maintenance is small, but it serves as an ideal model for energy-dependent molecular machines. The goal of this work is to describe the energetics of ClpA's interactions with both soluble and membrane-bound protein substrates. Green …
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Ironing Out the Host-fungal Interaction in Airway Epithelial Cells
… is needed by both the fungus and the host for cellular maintenance and survival, but tightly controlled iron regulation in the host is required to prevent oxidative stress and cell death. The research methods in this dissertation employ a systems biology approach, by incorporating mathematical …
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The effect of antibiotic resistance on bacterial cell maintenance In gram-negative bacteria
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-05-01
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Visualization and quantification of autophagy in primary gastrointestinal epithelia cell cultures.
Autophagy is an intracellular bulk degradation pathway which can be used during cellular maintenance to encapsulate and target intracellular content such as organelles and proteins to be degraded by the lysosome. The autophagosome is a double membrane vesicle which is used to encapsulate this …
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The somatic evolution of the canine transmissible venereal tumour
… expression in tumour cells is largely centred on cellular maintenance and replication. The sixth chapter explores signatures of natural selection in CTVT, including early ‘driver’ mutations and signals of selection for more recent mutations; the results reveal that CTVT largely evolves via genetic …