Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 31 for “"Cells--Growth"”.
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CdTe solar cells: growth phenomena and device performance
… the control of CdTe and CdS layers during their growth, with the understanding gained being implemented in the production of solar cells with enhanced performance. In particular the growth mechanisms for close space sublimation (CSS) — grown CdTe were evaluated as a function of processing gas …
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Roles of Zinc in Skeletal Muscle Cells Growth
Zinc deficiency impairs skeletal muscle growth in both humans and animals independently of decreased food intake. Insulin-like growth factor (IGF) is the primary regulator of postnatal muscle growth and there is substantial evidence that the effects of zinc deficiency alter IGF mediated muscle …
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Phytochemicals from Graviola fruit selectively inhibit breast cancer cells growth involving EGFR signaling pathway
… (GFE) on specific human breast cancer (BC) cells. GFE was found in our preliminary screening to selectively inhibit the growth of certain human BC cells (MDA-MB-468) but did not affect non-transformed breast epithelial MCF-10A cells. GFE treatment was very effective against the growth of …
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UNRAVELING TAZ REGULATION IN BREAST CANCER BY CRISPR SCREENING
… of breast tumors, endowing mammary gland cells with oncogenic features, as stemness properties, migration, invasion and chemoresistance. Yet, YAP/TAZ mutations or genetic alterations of their known upstream regulators are relatively rare, raising the question of how YAP/TAZ are upregulated …
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Interaction of Bdellovibrio Bacteriovorus and Host Bacteria
… pH 7.8, supplemented with 0.002 M CaCl2*2H 0. Growth of Bdellovibrio occurred within a wide pH range, with the optimum being from 7.5 to 8.5. No growth occurred at pH 6.5. The broad pH range may occur because a buffer per se is not required for growth and multiplication. Bdellovibrio failed to …
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Computational Systems Biology Analysis of Cell Reprogramming and Activation Dynamics
… of bacteria E.coli between normally-growing cells and persister cells (growth-arrested phenotype), and how this process can contribute to drug resistance. We built up a complex computational model capturing the molecular mechanism on both single cell level and population level. The paper also …
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Cell Growth Paramenters and Sister Chromatid Exchange Level in Fibroblasts from a Patient Diagnosed with Bloom Syndrome
… of the syndrome. This research compared the growth response to bovine pituitary fibroblast growth factor, the mitotic index, and the sister chromatid exchange level of the KB fibroblasts with normal and known Bloom Syndrome control fibroblasts. Procedure. The growth responses of the KB, …
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Advances in Bone Tissue Engineering
… these limitations. By combining bone forming cells, growth factors and scaffolding materials, this technique has the potential to generate custom made bone grafts. The main objectives for this thesis were to optimize the conditions for bone tissue engineering, to introduce new perspectives and …
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The Role of Glutamine and Mevalonate Pathway In Affecting The Stemness and Viability of Glioblastoma Stem Cells
… been suggested that the presence of cancer stem cells, which are relatively resistant to radiation and chemotherapy, may play a significant role in the recurrence of brain tumor. Understanding the biological property of glioblastoma stem cells is important to develop effective therapeutic …
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Computational modeling of tumor cell growth as a function of nutrient dynamics guided by time-resolved microscopy
… force reprogramming of metabolism in tumor cells. This metabolic reprogramming has been identified as a hallmark of cancer. This dissertation focuses on the development and validation of an experimental-mathematical approach that predicts how the dynamics of glucose and lactate influence …
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The effect of hypoxia and 3D culture conditions on heterogeneous ovarian cancer spheroids
… progression and the interaction between cancer cells with their unique microenvironment. Therefore, this work investigated the metabolic shift in the mouse model for progressive ovarian cancer, and evaluated the effects of hypoxic environment, spheroid formation as well as stromal vascular …
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Radiosensitization of Head & Neck Carcinoma Cells by Linifanib, A Receptor Tyrosine Kinase Inhibitor
… angiogenic factors such as vascular endothelial growth factor (VEGF). Since radiotherapy is one of the most commonly used treatments for HNSCC, it is imperative to identify the interactions between antiangiogenic therapy and radiotherapy, and to develop combination therapy to improve clinical …
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Characterization of a new miniaturized hollow-fiber bioreactor for cultivation of cell lines and primary cells to improve cytostatic drug testing in vitro
… with regard to transport characteristics and growth of leukemic cell lines (chapter 2). Cell and medium compartment are separated by dialysis membranes and oxygenation is accomplished using oxygenation membranes. Due to a transparent housing, cells can be observed by microscopy during culture. …
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A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in clear cell renal cell carcinoma
… of cellular networks on which ccRCC cells are highly dependent would facilitate the development of better diagnostic and/or therapeutic approaches for ccRCC. Super enhancers have been reported to drive the expression of critical transcription regulators in various biological contexts …
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Peptides can be utilized as amino acid sources for protein accretion and cell proliferation by cultured animal cells
… mammary epithelial and ovine myogenic satellite cells. Factors in serum that may be involved in regulating peptide utilization was investigated using MAC-T cells. Growth of MAC-T cells was studied in the presence of methionine-containing dipeptides with 6% desalted adult animal serum from …
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Mathematical and Experimental Investigation of Yeast Colony Development – A Model System for the Growth of Filamentous Fungi in Heterogeneous Environments
… were applied as model organisms to study the growth of fungal mycelia. When environmental conditions are chosen appropriately, yeast colonies are built up of well separated individual cells. Thus, in contrast to fungal mycelia the translocation of nutrients and information within the colony …
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The chemokine CCL2/CCR2 signaling mediates cancer associated fibroblasts-cancer cells interaction and promotes basal-like breast cancer progression
… fibroblasts (CAFs) are the most abundant stromal cells in breast cancer, but their function in cancer progression has not been fully understood. We previously identified that the chemokine CCL2 was highly expressed in breast cancer associated fibroblasts. CCL2 is known to recruit …
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Ursolic acid and oleanolic acid as novel therapeutic agents in breast cancer
… were studied in vitro in MCF-7 breast cancer cells and MCF10A breast cells. In this study the first aim was to establish the influence of OA and UA on cell growth and to see if opposing proliferation patterns could observed between the presumably ERɑ negative (ERɑ/ß - /+) MCF-10A and ERɑ …
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DEVELOPMENTAL REMODELING OF RELAY CELLS IN THE DORSAL LATERAL GENICULATE NUCLEUS (dLGN) OF THE MOUSE AND THE ROLE OF RETINAL INNERVATION
… connections made with thalamocortical relay cells. By contrast, little is known about relay cells and the factors that regulate the growth and establishment of their dendritic architecture. In many systems, such growth seems consistent with the synaptotrophic hypothesis which states that …
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