Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Cells -- Aging"”.
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Hematopoiesis: Functional Insights by Cell Fate Conversion
… is maintained by rare hematopoietic stem cells (HSCs) residing in the bone marrow (BM). HSCs may self-renew (the process whereby HSCs replicate to produce new HSCs) to preserve their own numbers, as well as initiate a highly coordinated hierarchical differentiation process that results in …
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A deep learning approach to estimate replicative lifespans from yeast cell images
… is an important model organism for cellular aging. A common metric for determining the lifespan of budding yeast cells is the replicative lifespan (RLS), how many times a mother cell divides in its lifetime. Traditionally, determining the RLS of yeast cells is a tedious manual process. To …
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Structural Analyses of Murine Histocompatibility Antigens
… 70,000-80,000 on mouse lymphocytes and leukemia cells. These components were also detected by a goat antiserum against the murine leukemia virus (MuLV) glycoprotein (gp70) and are therefore closely related to or identical with that viral protein. Further experiments suggest that factors such as …
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The effects of aging and transformation on the DNA, RNA, protein, and hydroxyproline content of fibroblasts (WI 38) in culture
The study of the aging process is the investigation as to how the passage of time affects cells, organs, and organisms. Aging is a very complex and incompletely understood phenomenon. This is reflected by the number of theories attributing aging to a variety of causative factors such as: (1) the …
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Molecular studies of longevity-associated genes in yeast and mammalian cells
Aging is a complex process affecting diverse organisms from bacteria to humans. Despite strong evolutionary arguments against the conservation of a single mechanism of aging, a variety of conserved single gene mutations have been found to extend life span and stave off aging in several different …
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Major Collateral Vessels Develop from Pre-existing Small Arteries through RAC2/NOX2 Independent Mechanisms
… the age-related impairment of collateral growth. Aging, like all cardiovascular disease risk factors is associated with elevated ROS and impaired collateral growth. Studies also suggest BMCs promote collateral growth by secreting paracrine factors but elevated ROS may affect the efficacy of BMCs. …