Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Cell-ECM interactions"”.
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Analyzing Interactions Between Cells And Extracellular Matrix By Atomic Force Microscopy
Interactions of cells with the extracellular matrix (ECM) have important roles in various physiological and pathological processes, including tissue morphogenesis during embryonic development, wound healing and tumor invasion. Although most of the proteins involved in cell-ECM interactions have …
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MODELING OF THE CHEMOMECHANICAL INTERACTIONS BETWEEN CELLS AND THE EXTRACELLULAR MATRIX
Understanding the complex interactions between cells and the extracellular matrix (ECM) is crucial. These interactions involve biochemical signals and mechanical forces that regulate vital cellular processes, including migration, differentiation, and proliferation. Disruptions in these interactions …
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The interaction of angiocidin and tissue transglutaminase
… source of these environmental signals is the interactions between the cell and the extracellular matrix (ECM). Cell adhesion molecules are found on the surface of all cells and play a role in cell-cell and cell-extracellular matrix interactions. Tissue transglutaminase is ubiquitously …
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The role of integrin mediated adhesion and signaling during Xenopus retinal development
<p>Integrins are the major family of cell adhesion receptors for extracellular matrix (ECM) components and are involved in cell-cell and cell-ECM adhesion. Integrins also participate in cytoskeletal rearrangements, activation of signal transductions, and co-regulation of growth factor …
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Proteomic Analysis of Three Dimensional Organotypic Liver Models
… for understanding hepatic functions and intercellular communication processes. Bottom-up shotgun proteomic analysis of the hepatic cells can lend insight into such processes. This technique employs liquid chromatography-tandem mass spectrometry (LC-MS/MS) for relative quantification of protein …
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The role of the mechanical microenvironment in regulation of cholangiocyte specification and tubulogenesis
… evidence highlights the influence of the extracellular matrix (ECM) on cell fate and functionality associated with ageing, development and disease (Segel et al. 2019; Bansaccal et al. 2023). Despite most studies emphasising ECM stiffness, recent insights suggest a cooperative role of ECM ligand …
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Characterization of Meta-Keratin Biomaterials Derived from Human Hair: Applications for Fiber Development
… biocompatibility and ability to regulate cellular behavior. The main objective of this dissertation work was to test the effect of increased surface area on the biological characteristics of human hair-derived keratin biomaterials. Since the bioactivity of keratin materials is believed to …
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Investigating the impact of gold nanoparticles on cells: from transcription to behavior
… therapy has motivated numerous analyses of their interactions with biomolecules, cells, animals, humans and the environment.1,2 A vast majority of studies aimed at gaining a better understanding of how cells interact with and are influenced by Au NPs have focused mainly on measuring cytotoxicity …
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Investigating the control of epithelial polarisation in human kidney organoids
… of polarity, where initially unpolarised cells polarise and orient themselves with respect to each other, swapping out a mesenchymal front-back polarity for an epithelial apical-basal polarity, concomitant with the establishment of intercellular junctions and adherence to an underlying …
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Cytoskeletal Remodeling in Fibrous Environments to Study Pathophysiology
Mechanical interactions of cells with their immediately surrounding extracellular matrix (ECM) is now known to be critical in pathophysiology. For example, during cancer progression, while uncontrollable cell division leads to tumor formation, the subsequent metastatic migration of cells from the …