Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Cell surface proteome"”.
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Investigating the function of the hereditary spastic paraplegia protein spastin in the endomembrane system
… well as to analyse the resulting effects on the cell surface proteome. Through this work, I have shown that spastin functions to mediate the fission of endosomal recycling tubule and have confirmed spastin’s localisation to ER exit sites, but show using synchronised secretion assays that spastin …
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Identification of surface protein complexes of Streptococcus pyogenes through protein microarray technology
… the composition and structure of the bacterial cell-surface proteome and its complexes can provide an invaluable tool for its comprehensive understanding. The knowledge of protein complexes composition and structure could offer new, more effective targets for a more specific and consequently …
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Analysis of the Tumour Microenvironment in CLL
… to obtain a better understanding of complex cellular systems in Chronic Lymphocytic Leukaemia (CLL).CLL is a cancer of the blood which affects B cells. CLL cells accumulate quickly in the body but die rapidly by apoptosis when cultured in the lab, suggesting that CLL cell survival can be …
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Single cell -omic landscapes in normal and perturbed haematopoiesis
The use of single cell genomics technologies to generate atlases of healthy tissues has served both as a valuable comparator resource for perturbed datasets, and to permit the discovery of novel biological processes in the differentiation of stem cells into mature tissues. Large scale profiling of …
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Cell Wall/Surface Proteome of Candida albicans: its Application in Rapid Identification of Yeast Species by Mass Signature and Characterization by in vitro and in vivo Chemical Labelings
… is impaired (such as those in HIV patients). Cell surface of C. albicans is the frontier where initial interplay between host-pathogen takes place and therefore is of great importance in understanding the mechanism of hostpathogen interaction. MALDI-TOF-MS analysis of intact fungal cells …