Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Cell spheroid"”.
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Studying the Role of Mechanical Properties of Cancer Cells in Tumour Detachment, Migration and Secondary Tumour Formation
Tumour cell detachment, migration and invasion, and secondary tumour formation are critical oncogenic processes during cancer metastasis. Although several molecular mechanisms have been reported to facilitate metastasis, it remains elusive how cellular mechanics contribute to these processes. The …
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Microfluidic-generated Double Emulsions for Cell Study, Drug Delivery and Particle Therapeutics Fabrication
… the application of DE as a micro-incubator for cellular studies such genetic circuit behavior and performance in bacterial cells cultured in DE droplets and formation of 3D mammalian cell spheroid. In chapter 4, we will show the successful application of DE as drug carriers for intranasal drug …
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Engineered 3D microenvironments to understand and direct liver progenitor and cancer cell fate
The cellular microenvironment encompasses every chemical and physical factor surrounding a cell, including all other cells, cell-cell and cell-extracellular matrix (ECM) signaling interactions and any detectible change in conditions. As the interplay between every component of the microenvironment …
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THE INFLUENCE OF MELANOMA STEM CELLS ON TUMOR MICROENVIRONMENT REMODELING: EXPERIMENTAL INSIGHTS FROM IN VITRO STUDIES
Cancer stem cells (SCs) constitute a small group of tumor cells with SC-like properties, such as selfrenewal and resistance to conventional therapies. In melanoma, it is now well established that cancer SCs play a pivotal role in driving tumor initiation, progression and therapeutic resistance, …