Global ETD Search
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Showing 1 to 5 of 5 for “"Cell size homeostasis"”.
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Evaluating the role of the fission yeast cyclin B Cdc13 in cell size homeostasis
Most cellular proteins retain a stable concentration as cells grow and divide, but there are exceptions. Some cell cycle regulators change in concentration with cell size. In fission yeast, Cdc13 (cyclin B), an important activator of the core cell cycle kinase Cdc2 (CDK1), increases in …
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On connections between metazoan cellular metabolism and cell size
All animal cells maintain cell size homeostasis, where cell growth (increase in size) is balanced with proliferation (reduction in size via cell division). Yet, different cell types have different sizes and there are physiologically relevant situations where animal cells undergo major cell size …
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The role of the transcription factor JAGGED in early floral organogenesis
… organ primordia from pools of undifferentiated cells requires coordinated cytoplasmic growth, oriented cell wall extension, and cell cycle progression. It is debated which of these processes are primary drivers for organ morphogenesis and directly targeted by developmental regulators. The single …
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Control of gene expression by cell size
… whole chromosome sets in the genome, is a common cellular state in evolution, development and disease. Polyploidy enlarges cell size and alters gene expression, producing novel phenotypes and functions. Although many polyploid cell types have been discovered, it is not clear how polyploidy changes …
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The role of the environmental stress response in aneuploid and cell cycle-arrested budding yeast
Size matters in eukaryotic cells. Inability to maintain cell size homeostasis, or the coordination between growth and division, has direct consequences on cellular functions and fitness. Eukaryotic cells have developed mechanisms to ensure proper coordination of biomass accumulation and cell cycle …