Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 289 for “"Cell membranes"”.
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Optical rheology for live cell membranes
… retrieving the full viscoelastic information of cell membrane material properties. Red blood cells (RBC) are chosen for this study because of their simple structure, which consists of a bi-layer cell membrane supported by a cytoskeleton enclosing a homogeneous fluid. The full complex modulus of …
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Studies on Ehrlich Ascites Tumor Cell Membranes
Made available in DSpace on 2014-12-10T22:38:16Z (GMT). No. of bitstreams: 1 7121097.pdf: 5532283 bytes, checksum: 5905d2c809d596373ddf2873ba4876c8 (MD5) Previous issue date: 1971
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Engineering artificial cell membranes by Ting F. Zhu.
… division are essential biological processes of cellular life. A crucial question concerning the origin of cellular life is how primitive cells (protocells) lacking complex biological machinery could grow and divide. To address this question, we first developed an effective method for preparing …
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CONTROLLING BIOFILM AND PERSISTER CELLS BY TARGETING CELL MEMBRANES
… is persister formation, by which bacterial cells enter a metabolically inactive stage and become highly tolerant to essentially all antibiotics, even at the concentrations that are hundreds of times higher than the lethal dose required to kill normal planktonic cells of the same strain. …
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Studies on the red blood cell membranes and their acetylcholinesterace
… of the structure and the properties of the RBC membranes, investigations on the localization and the nature of association of the ACHE molecules on them could be quite profitable . It was therefore decided to carry on some investigations along these lines. The results obtained are presented in …
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Monitoring Biological Events on Native Cell Membranes with Organic Bioelectronics
… than half of currently approved drugs target cell membranes, studying drug interactions with cell membranes is one of the key factors in understanding drug cytotoxicity and efficacy. The recently developed membrane-on-a-chip system, involving cell-derived supported lipid bilayers (SLBs) …
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Pipeline for semi-automatic segmentation of confluent endothelial cell membranes
Changes in cell morphology are important indicators of underlying biological changes. As endothelial cells (EC) heterogeneously respond to stimuli, we seek to quantify EC morphologic heterogeneity and relate it to transcriptome phenotypes; however, existing semi-automatic methods for quantifying …
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Water transport in fuel cell membranes measured by laser interferometry
… of proton transfer is not active in the membranes with low water content. The successful evaluation of these coefficients has not only showed the validity of this new technique, which is confirmed by the agreement between the measured coefficients and the models proposed to explain the …
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Investigation of Shorting by Penetration in Pem Fuel Cell Membranes
… form of early failure commonly found in PEM fuel cells. In order to improve the durability and thus the commercial potential for PEM fuel cells, this form of failure must be understood and mitigated. This research investigates whether complete penetration is the most likely cause of shorting and …
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Analysis of the organization and dynamics of proteins in cell membranes
Cells communicate with the outside world through membrane receptors that recognize one of many possible stimuli (hormones, antibodies, peptides) in the extracellular environment and translate this information to intracellular responses. Stimulation of the cells produces changes in the organization …
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Markov random field modeling of the spatial distribution of proteins on cell membranes
Cell membranes display a range of receptors that bind ligands and activate signaling pathways. Signaling is characterized by dramatic changes in membrane molecular topography, including the co-clustering of receptors with signaling molecules and the segregation of other signaling molecules away …
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Neutron scattering studies of water diffusion near the interface of model cell membranes
… and perform a variety of tasks that help govern cellular activity. Their structure, insertion mechanisms, and function largely depend on the interactions between peptide-lipid domains and the hydrating water. Therefore, the dynamics of the membrane-associated water and its interaction with …
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Biomechanical structure-function relationships of collagen tissues, B Cell membranes, and amyloid fibers
… comprised of wavy fibers (~ 1 mm), B lymphocyte membranes (~ 1 [mu]m), and amyloid protein fibers (~ 1 nm). The initial portion of this thesis addresses the mechanics of fibrous collagen tissues such as ligaments, tendons, and pericardium that serve as load bearing components in biological …
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Multi-Scale Modelling of Host-Microbe Interactions: From Cell Membranes to Multi-Cellular Gut Models
… mechanical and biophysical cues, immune cells and supporting longer-term co-culture of microbiota, amongst others. Nevertheless, platforms which combine all of these and more faithfully represent the intestinal tract cells are still lacking. Given the complexity of the intestinal tract, …
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Anticancer a-helical peptides and their structure / function relationships underpinning their interactions with tumour cell membranes
… to the discovery of toxic peptides with cancer cell specificity. Extensive research is therefore required to determine how these anticancer peptides (ACPs) function and how their structural characteristics relate to both specificity and efficacy. An ACP database comprising of 158 peptides was …
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Development of a non-living model system for cell membranes and investigation of its mechanical and tribological properties
… and developed a non-living model system for cell membranes which is suitable for elucidating interactions between NMs and living cells. In contrast to existing model systems for cell membranes, PAAm hydrogel was used as soft support for the lipid. Grafting of lipid with PAAm was achieved …
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Development of new tools to study drug-lipid interactions and their application to investigating amphotericin b's association with model cell membranes
… antifungal drug amphotericin B (AmB) with model cell membranes was studied and new techniques of measuring this interaction using electrochemical and/or spectroscopic methods were developed. Two model cell membrane systems were used: sterol-free lipid monolayers adsorbed to a Hg electrode and …
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