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Showing 1 to 8 of 8 for “"Cell intercalation"”.
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Quantitative Aspects of Interface Remodeling During Germband Extension
<p>Oriented cell intercalation is an essential developmental process that shapes tissue morphologies through the directional insertion of cells between their neighbors. Intercalary behaviors in the early <em>Drosophila</em> embryo occur through a remodeling of cell topologies, with cells …
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A Role for Dynamin-Dependent Endocytosis During Drosophila Gastrulation
… higher organisms, is the directed migration of cells into layers that will establish various tissues targeted to become anatomical structures. This process is accomplished through another conserved morphogenetic event, known as cell intercalation. Early in development, this movement of cells …
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Regulation of Actin Dynamics During Drosophila Germband Extension
… as germband extension and is mainly driven by cell intercalation or neighbor exchange by planar polarized cell-cell interface contraction to shorten the tissue along the dorsal-ventral axis. In this thesis, I show that interface contraction consists of phases of fast interface shortening and …
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Automatic Cell Tracking For Studying Large Epithelial Sheets Of Cells And Its Application To Chicken Gastrulation
… vortical flows that involve an order of >200,000 cells. During this self-organised process individual epithelial cells are migrating in a highly coordinated manner. The cell behaviours driving the flows and migration are unknown due to the lack of high resolution time lapse sequences showing each …
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Learning from Disorder and Noise in Physical Biology
… and still serve distinct purposes within the cell. At the scale of gene regulation, realistic <em>in vivo</em> conditions produce stochastic fluctuations in gene expression that can lead to advantageous bet-hedging strategies, but can be difficult to characterize using a deterministic …
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Forces Generated by Cell Intercalculation Tow Epidermal Sheets in Mammalian Tissue Morphogenesis
… and individual movements—are processes of cell migration. Throughout our lives, cell migration plays a role in the maintenance and regeneration of our tissues, and even in the development and progression of disease. To carry out the complex tasks of development and tissue morphogenesis, …
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Quantification of Dynamic Epithelial Sheet Architecture in Botryllus Schlosseri Using 2-D & 3-D Image Analysis
… morphology. In normal vessels, we found the cells to be planar polarized with curvature - dependent axial elongation of cells, and a robust circumferential alignment of actin bundles. While we found no measurable differences in morphology between normal and BAPN treated vessels, FAK-inhibited …
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Investigating the cell surface code for compartment boundary formation in Drosophila embryos
During animal development, the separation of cells of different identity is crucial for the formation and function of tissues and organs. Tissues are compartmentalised to ensure organisation remains during dynamic processes, such as cell division and cell rearrangement. At Drosophila compartment …