Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Cell extrusion"”.
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Genetic regulation of cell extrusion in caenorhabditis elegans
Programmed elimination of cells occurs during animal development and homeostasis to maintain appropriate cell numbers. One evolutionarily conserved method by which organisms eliminate cells in a programmed manner is by cell-autonomous activation of the caspase-mediated apoptosis pathway, which …
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The Pro-Apoptotic Function of CED-9 Requires a CED-9-CED-4 Interaction
Apoptosis is a fundamental, conserved process of cell death required for animal development and tissue homeostasis. In Caenorhabditis elegans apoptosis is inhibited by the BCL-2 homolog CED-9. In addition to its canonical anti-apoptotic role, CED-9 possesses an apparent proapoptotic function, …
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Development of Novel Methods to Study Host-Microbe Interactions In The Larval Zebrafish Gastrointestinal Tract
… stressors, undergoes rapid turnover. Extrusion, the process by which excess or compromised cells are shed from epithelial layers, is vital to maintaining barrier integrity. Despite extensive research in various models, including tissue culture cells, <em>Drosophila</em>, and the tail …
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Cellular Morphodynamics Reveals Divergent Mechanisms of Gastrulation in Insects
During embryonic development, dynamic cellular rearrangements collectively result in tissue morphogenesis. One fundamental morphogenetic process is tissue internalisation, of which the earliest occurrence drives mesoderm gastrulation in a wide variety of organisms. In both the fly Drosophila …