Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Cell cycle synchronisation"”.
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Malignant Glioma: Chemosensitivity testing and Biomarkers
… Increased frequency of application as well as cell cycle synchronisation of glioma cell lines were found to improve the kill efficiency of Temozolomide. Six molecules were considered as potential biomarkers. All of them were found to be effective at predicting the presence of malignant gliomas. …
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Mapping the cell cycle-dependent centrosomal interactome
… and precisely ordered events must occur for cells to multiply. Understanding the dynamic interactions of proteins driving this process are crucial for deciphering cell fate. The centrosome is a non-membrane-bound organelle that acts as the primary microtubule organizing centre and is believed …
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SMAD2/3 - FOXH1 regulation during cell cycle progression upon differentiation
… and to later produce the correct amounts of each cell type. While the characteristics of cell cycle regulation in pluripotent and differentiated cells have been well described, the way they coordinate cell fate acquisition is only beginning to be elucidated. Indeed, the activity of TGFβ signalling …
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The interplay of global chromosomal organisation, promoter-enhancer interactions and transcription
All somatic cells within an organism contain the same genetic material, yet they display pronounced differences in function and morphology. Precise control of gene expression is of fundamental importance to allow cells to properly develop, maintain homeostasis, and respond to external stimuli. The …