Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Cell Population Dynamics"”.
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Modeling Stem Cell Population Dynamics
… to new understandings of complicated cell mechanisms and tissue physiology. Indeed, even single cell or small tissue samples are complex dynamic systems that adapt to environmental challenges in space and time which is poorly understood. Mathematical models and computer simulations can …
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Developing EasySci, a High-Throughput and Low-Cost Single-Cell Genomic Technique, to Study Aging and Alzheimer's Disease in Human and Mouse Brain
<p>Previous single-cell methods are limited by their relatively low throughput and high costs. This prevents most laboratories from performing large-scale cell profiling, complicating the understanding of rare cell type contributions to aging and disease. Moreover, these methods often focus on the …
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An insulin-like peptide regulates size and adult stem cells in planarians
… an opportunity to readily observe adult stem cell population dynamics in response to nutritional cues. We explore the role of insulin signaling in S. mediterranea. We disrupt insulin signaling via RNA interference and show that animals, despite eating, degrow similarly to starved animals. …
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Cue, signal, response analysis of murine embryonic stem cell differentiation : multivariable analysis of cytokine and ECM effects on commitment to differentiation
The highly complex nature of developmental cell fate decisions is exemplified by murine embryonic stem cell (ES cell) differentiation, for which almost two decades of study has identified a small set of putative individual molecular cues which are difficult to generalize broadly or discern …
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MODELLING CELL POPULATION GROWTH
… by the characteristics of the tissue’s extracellular matrix and constituent cells, including, but not limited to, cell membrane stiffness, cell cytoskeleton mechanical properties, and the intensity and distribution of focal adhesions over the cell membrane. To compute and study the mechanical …