Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Cell Dissociation"”.
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The role of PAK6 in HGF-induced prostate cancer cell migration
Cell migration plays a significant role in carcinoma metastasis in which cancer cells move from the primary site and establish tumours at a secondary location. During tumour progression cancer cells can assume a migratory phenotype which is characterised by cell-cell dissociation and single cells …
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Developing cultivated mollusks through establishing primary cell culture methods of Eastern Oyster, Crassostrea virginica, as a model bivalve
… Cultivated seafood is made by growing animal cells in vitro using stem cells for edible food, eliminating the need to raise the entire animal. A crucial first step in developing cultivated seafood is creating a well-characterized cell line that can continuously grow and differentiate into …
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Molecular factors influencing epithelial-mesenchymal transition in breast cancer
… processes are also implicated in carcinoma cell invasion and the progression of breast carcinoma to metastasis. In a cell model system for mammary carcinogenesis it has previously been shown that signaling from the oncogenic receptor tyrosine kinase c-erbB2 (HER2), frequently overexpressed …
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Chemesthesis in the Earthworm, Lumbricus terrestris: The search for TRP Channels
… immunohistochemical, behavioral and cell dissociation/calcium imaging techniques. We obtained responses from segmental nerves to tactile stimulus, 50mM AITC and pH 3.8, 4.0 and 4.2. Some cells in the epidermis displayed positive immunoreactivity for Drosophila and human TRPA1 …
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Dietary regulation of myelopoiesis and stromal cell isolation
… chloride did not alter monocyte, granulocyte, T cell, B cell, or NK cell distributions in blood. In spleen, 10% sodium chloride did reduce the presence of NK cells but had minimal effect on other cell populations. In bone marrow, 10% sodium chloride increased the presence of T cells and both …
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Germ lineage specification from a pluripotent primitive ectoderm-like substrate: a role for cell-cell contacts.
… development a small number of pluripotent cells proliferate and differentiate to give rise to all the mature cell types of the organism. Among the earliest differentiation events is the process of gastrulation, in which pluripotent primitive ectoderm cells form the three germ lineages, …
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A Microfluidic Tissue Array (µFTA) For Personalized Medicine using Tumor Biopsies
… originate from as small as a single deregulated cell, the disease itself manifests itself with several more complexities beyond tumorigenic cells only. The tumor microenvironment itself – from the extracellular matrix to stromal cells - cooperate with tumor cells in a symbiotic manner towards …
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Safeguarding the mitochondrial genome: identifying components of the mtDNA repair machinery
… to mitochondria in Drosophila and human cells, suggesting that nuclear DNA repair proteins could be co-opted to maintain mitochondrial genome integrity. I performed phenotypic assays and showed that compromising REC function affects organismal fitness during ageing. Additionally, I tagged …